Chronic kidney disease (CKD) has a high prevalence in the general population and is
associated with high mortality; a need therefore exists for better biomarkers for diagnosis …

The use of electronic cigarettes (e-cigs) is increasing rapidly, but their effects on lung toxicity
are largely unknown. Smoking is a well-established cause of lung cancer and respiratory …

The serum metabolome contains a plethora of biomarkers and causative agents of various
diseases, some of which are endogenously produced and some that have been taken up …

A critical question facing the field of metabolomics is whether data obtained from different
centers can be effectively compared and combined. An important aspect of this is the …

Context: Obesity and related diseases have become a global public health burden.
Identifying biomarkers will lead to a better understanding of the underlying mechanisms …

OBJECTIVE Metformin is used as a first-line oral treatment for type 2 diabetes (T2D).
However, the underlying mechanism is not fully understood. Here, we aimed to …

Metabolomics is a rapidly expanding field of systems biology that is gaining significant
attention in many areas of biomedical research. Also known as metabonomics, it comprises …

Abstract Background Metabolic Syndrome (MetS) is characterized by risk factors such as
abdominal obesity, hypertriglyceridemia, low high-density lipoprotein cholesterol (HDL-C) …

This study conducted comprehensive and comparative metabolic and lipidomic profiling of a
human epithelial breast cell line (MCF-10A), a slightly metastatic (MCF-7), and a highly …

Background: Identifying circulating metabolites related to cigarette smoking may provide
insight into the biological mechanisms of smoking-related diseases and the nature of …