Cubosomes: the next generation of smart lipid nanoparticles?

HMG Barriga, MN Holme… - Angewandte Chemie …, 2019 - Wiley Online Library
Cubosomes are highly stable nanoparticles formed from the lipid cubic phase and stabilized
by a polymer based outer corona. Bicontinuous lipid cubic phases consist of a single lipid …

Cubosomes as an emerging platform for drug delivery: A review of the state of the art

MAS Abourehab, MJ Ansari, A Singh… - Journal of Materials …, 2022 - pubs.rsc.org
Lipid-based drug-delivery nanoparticles, including non-lamellar-type, mesophasic
nanostructured materials of lyotropic liquid crystals (LLCs), have been a topic of interest for …

Non-lamellar lyotropic liquid crystalline lipid nanoparticles for the next generation of nanomedicine

J Zhai, C Fong, N Tran, CJ Drummond - ACS nano, 2019 - ACS Publications
Nonlamellar lyotropic liquid crystalline (LLC) lipid nanomaterials have emerged as a
promising class of advanced materials for the next generation of nanomedicine, comprising …

Nature‐Inspired design and application of lipidic lyotropic liquid crystals

R Mezzenga, JM Seddon, CJ Drummond… - Advanced …, 2019 - Wiley Online Library
Amphiphilic lipids aggregate in aqueous solution into a variety of structural arrangements.
Among the plethora of ordered structures that have been reported, many have also been …

Advances in lyotropic liquid crystal systems for skin drug delivery

AVP Silvestrini, AL Caron, J Viegas… - Expert Opinion on …, 2020 - Taylor & Francis
ABSTRACT Introduction Lyotropic liquid crystals (LLCs) are organized mesophases with
intermediate properties between liquids and solids. The LLC and its liquid crystalline …

Cubosomes and hexosomes as novel nanocarriers for bioactive compounds

C Tan, SF Hosseini, SM Jafari - Journal of Agricultural and Food …, 2022 - ACS Publications
Cubosomes and hexosomes are nanostructured liquid crystalline particles, known as
biocompatible nanocarriers for drug delivery. In recent years, there has been good interest …

Paclitaxel-loaded self-assembled lipid nanoparticles as targeted drug delivery systems for the treatment of aggressive ovarian cancer

J Zhai, RB Luwor, N Ahmed, R Escalona… - … applied materials & …, 2018 - ACS Publications
Chemotherapy using cytotoxic agents, such as paclitaxel (PTX), is one of the most effective
treatments for advanced ovarian cancer. However, due to nonspecific targeting of the drug …

[HTML][HTML] Lipidic lyotropic liquid crystals: Insights on biomedical applications

G Blanco-Fernández, B Blanco-Fernandez… - Advances in Colloid and …, 2023 - Elsevier
Liquid crystals (LCs) possess unique physicochemical properties, translatable into a wide
range of applications. To date, lipidic lyotropic LCs (LLCs) have been extensively explored …

Self‐assembled nanostructured lipid systems: is there a link between structure and cytotoxicity?

A Tan, L Hong, JD Du, BJ Boyd - Advanced Science, 2019 - Wiley Online Library
Self‐assembly of lipid‐based liquid crystalline (LLC) nanoparticles is a formulation art
arising from the hydrophilic–lipophilic qualities and the geometric packing of amphiphilic …

Cubosomes stabilized by a polyphosphoester-analog of Pluronic F127 with reduced cytotoxicity

M Fornasier, S Biffi, B Bortot, P Macor, A Manhart… - Journal of colloid and …, 2020 - Elsevier
Lyotropic liquid crystalline nanoparticles with bicontinuous cubic internal nanostructure,
known as cubosomes, have been proposed as nanocarriers in various medical applications …