Nanotoxicity: an interplay of oxidative stress, inflammation and cell death

P Khanna, C Ong, BH Bay, GH Baeg - Nanomaterials, 2015 - mdpi.com
Nanoparticles are emerging as a useful tool for a wide variety of biomedical, consumer and
instrumental applications that include drug delivery systems, biosensors and environmental …

The role of zinc and zinc homeostasis in macrophage function

H Gao, W Dai, L Zhao, J Min… - Journal of immunology …, 2018 - Wiley Online Library
Zinc has long been recognized as an essential trace element, playing roles in the growth
and development of all living organisms. In recent decades, zinc homeostasis was also …

Redox interactions and genotoxicity of metal-based nanoparticles: A comprehensive review

K Mortezaee, M Najafi, H Samadian, H Barabadi… - Chemico-biological …, 2019 - Elsevier
Nanotechnology is a growing science that may provide several new applications for
medicine, food preservation, diagnostic technologies, and sanitation. Despite its beneficial …

[HTML][HTML] Biological effects of nanoparticles on macrophage polarization in the tumor microenvironment

D Reichel, M Tripathi, JM Perez - Nanotheranostics, 2019 - ncbi.nlm.nih.gov
Biological interactions between tumor-associated macrophages (TAMs), cancer cells and
other cells within the tumor microenvironment contribute to tumorigenesis, tumor growth …

The current state of nanoparticle-induced macrophage polarization and reprogramming research

X Miao, X Leng, Q Zhang - International Journal of Molecular Sciences, 2017 - mdpi.com
Macrophages are vital regulators of the host defense in organisms. In response to different
local microenvironments, resting macrophages (M0) can be polarized into different …

Zinc oxide nanoparticles harness autophagy to induce cell death in lung epithelial cells

J Zhang, X Qin, B Wang, G Xu, Z Qin, J Wang… - Cell death & …, 2017 - nature.com
Although zinc oxide nanoparticles (ZnONPs) are widely used, they have raised concerns of
toxicity in humans. Previous studies have indicated that reactive oxygen species (ROS) and …

Toxic effects and involved molecular pathways of nanoparticles on cells and subcellular organelles

N Liu, M Tang - Journal of Applied Toxicology, 2020 - Wiley Online Library
Owing to the increasing application of engineered nanoparticles (NPs), besides the
workplace, human beings are also exposed to NPs from nanoproducts through the skin …

Food additive zinc oxide nanoparticles: dissolution, interaction, fate, cytotoxicity, and oral toxicity

SM Youn, SJ Choi - International journal of molecular sciences, 2022 - mdpi.com
Food additive zinc oxide (ZnO) nanoparticles (NPs) are widely used as a Zn supplement in
the food and agriculture industries. However, ZnO NPs are directly added to complex food …

Potential risks and benefits of zinc oxide nanoparticles: a systematic review

S Keerthana, A Kumar - Critical Reviews in Toxicology, 2020 - Taylor & Francis
Zinc oxide nanoparticles are well-known metal oxide nanoparticles having numbers of
applications in the field of cosmetology, medicine, and chemistry. However, the number of …

Understanding nanoparticle toxicity to direct a safe-by-design approach in cancer nanomedicine

JA Damasco, S Ravi, JD Perez, DE Hagaman… - Nanomaterials, 2020 - mdpi.com
Nanomedicine is a rapidly growing field that uses nanomaterials for the diagnosis, treatment
and prevention of various diseases, including cancer. Various biocompatible nanoplatforms …