Multiscale simulations of biological membranes: the challenge to understand biological phenomena in a living substance

G Enkavi, M Javanainen, W Kulig, T Róg… - Chemical …, 2019 - ACS Publications
Biological membranes are tricky to investigate. They are complex in terms of molecular
composition and structure, functional over a wide range of time scales, and characterized by …

Mechanism of membrane fusion: interplay of lipid and peptide

A Joardar, GP Pattnaik, H Chakraborty - The Journal of Membrane Biology, 2022 - Springer
Membrane fusion is an essential process for the survival of eukaryotes and the entry of
enveloped viruses into host cells. A proper understanding of the mechanism of membrane …

Insulin-loaded liposomes packaged in alginate hydrogels promote the oral bioavailability of insulin

H Wu, J Nan, L Yang, HJ Park, J Li - Journal of Controlled Release, 2023 - Elsevier
Compared to subcutaneous injections, oral administration of insulin would be a preferred
route of drug administration for diabetic patients. For oral delivery, both liposomes and …

Repurposing the Ebola and Marburg Virus Inhibitors Tilorone, Quinacrine, and Pyronaridine: In Vitro Activity against SARS-CoV-2 and Potential Mechanisms

AC Puhl, EJ Fritch, TR Lane, LV Tse, BL Yount… - ACS …, 2021 - ACS Publications
Severe acute respiratory coronavirus 2 (SARS-CoV-2) is a newly identified virus that has
resulted in over 2.5 million deaths globally and over 116 million cases globally in March …

Self-propelling targeted magneto-nanobots for deep tumor penetration and pH-responsive intracellular drug delivery

SS Andhari, RD Wavhale, KD Dhobale, BV Tawade… - Scientific reports, 2020 - nature.com
Self-propelling magnetic nanorobots capable of intrinsic-navigation in biological fluids with
enhanced pharmacokinetics and deeper tissue penetration implicates promising strategy in …

Self-division of giant vesicles driven by an internal enzymatic reaction

Y Miele, Z Medveczky, G Holló, B Tegze, I Derényi… - Chemical …, 2020 - pubs.rsc.org
Self-division is one of the most common phenomena in living systems and one of the most
important properties of life driven by internal mechanisms of cells. Design and engineering …

Behaviour of liposomes loaded with bovine serum albumin during in vitro digestion

W Liu, A Ye, W Liu, C Liu, J Han, H Singh - Food chemistry, 2015 - Elsevier
This study examined the stability of liposomes loaded with negatively charged protein
(bovine serum albumin, BSA) during in vitro digestion. Zeta-potential and morphology …

Recent development in computer simulations of lipid bilayers

AP Lyubartsev, AL Rabinovich - Soft Matter, 2011 - pubs.rsc.org
Rapid development of computer power during the last decade has made molecular
simulations of lipid bilayers feasible for many research groups, which, together with the …

Photoactivatable lipid probes for studying biomembranes by photoaffinity labeling

Y Xia, L Peng - Chemical reviews, 2013 - ACS Publications
1.1. Biomembranes Biological membranes consist mainly of lipids and proteins (Figure 1)
and form the boundaries of all cells. The major lipids present in biomembranes are …

Lipid monolayer spontaneous curvatures: A collection of published values

MK Dymond - Chemistry and Physics of Lipids, 2021 - Elsevier
Lipid monolayer spontaneous curvatures (or lipid intrinsic curvatures) are one of several
material properties of lipids that enable the stored curvature elastic energy in a lipid …