Overview of serpin B9 and its roles in cancer

WJ Wang, J Wang, C Ouyang, C Chen… - Oncology …, 2021 - spandidos-publications.com
Serine proteinase inhibitor B9 (serpin B9) is a member of the serine protease inhibitor
superfamily, which is widely found in animals, plants and microorganisms. Serpin B9 has …

Natural products as a promising therapeutic strategy to target cancer stem cells

M Erkisa, M Sariman, OG Geyik, C Geyik… - Current Medicinal …, 2022 - ingentaconnect.com
Cancer remains a deadly disease, and its treatment desperately needs to be managed
through novel, rapidly advancing strategies. Most cancer cases eventually develop into …

NUMB suppression by miR-9-5P enhances CD44+ prostate cancer stem cell growth and metastasis

X Wang, J Cai, L Zhao, D Zhang, G Xu, J Hu… - Scientific Reports, 2021 - nature.com
Experimental and clinical studies over the past two decades have provided overwhelming
evidence that human cancers, including prostate cancer (PCa), harbor cancer stem cells …

siRNA‐induced CD44 knockdown suppresses the proliferation and invasion of colorectal cancer stem cells through inhibiting epithelial–mesenchymal transition

W Zou, Y Zhang, G Bai, J Zhuang, L Wei… - Journal of Cellular …, 2022 - Wiley Online Library
CD44 has shown prognostic values and promising therapeutic potential in multiple human
cancers; however, the effects of CD44 silencing on biological behaviors of cancer stem cells …

Biological heterogeneity of chondrosarcoma: from (Epi) genetics through stemness and deregulated signaling to immunophenotype

A Zając, SK Król, P Rutkowski, AM Czarnecka - Cancers, 2021 - mdpi.com
Simple Summary Chondrosarcoma (ChS) is the second most frequently diagnosed
malignant bone tumor of cartilaginous origin and is generally resistant to standard treatment …

Phase separation in epigenetics and cancer stem cells

C Xiao, G Wu, P Chen, L Gao, G Chen… - Frontiers in oncology, 2022 - frontiersin.org
Accumulating evidence indicates that liquid–liquid phase separation (LLPS) is the basis of
the formation of membrane-less compartments in cells. This biomolecular condensate …

The Impact of Cancer Stem Cells in Colorectal Cancer

P Radu, M Zurzu, A Tigora, V Paic, M Bratucu… - International Journal of …, 2024 - mdpi.com
Despite incessant research, colorectal cancer (CRC) is still one of the most common causes
of fatality in both men and women worldwide. Over time, advancements in medical …

Exosomal lncRNA Mir100hg derived from cancer stem cells enhance glycolysis and promote metastasis of melanoma through miR-16-5p and miR-23a-3p

J Tan, Y Tang, B Li, L Shi, Y Zhang, Y Chen… - Experimental Cell …, 2024 - Elsevier
Increasing evidence demonstrate that the significant role of long non-coding RNA (lncRNA)
in metastasis and the remodeling of the tumor microenvironment. However, the precise …

Cancer Stem Cells in the Head and Neck Cancers

EJ Kilmister, ST Tan - Atlas of Extreme Facial Cancer: Challenges and …, 2022 - Springer
Cancer stem cells (CSCs) have been identified in many cancer types, including head and
neck cutaneous squamous cell carcinoma and malignant melanoma. These CSCs divide …

[PDF][PDF] Serpin B9 与肿瘤及肿瘤干细胞的研究进展

王文君, 王娇, 叶小群 - 肿瘤, 2021 - tumorsci.org
丝氨酸蛋白酶抑制剂B9 (serine proteinase inhibitor B9, Serpin B9) 是丝氨酸蛋白酶抑制剂超
家族成员之一, 广泛存在于动物, 植物和微生物体内, 其通过抑制淋巴细胞释放颗粒酶B …