Transposable elements (TEs) promote genetic innovation but also threaten genome stability.
Despite multiple layers of host defence, TEs actively shape mammalian-specific …

It has recently become apparent that RNA, itself the product of transcription, is a major
regulator of the transcriptional process. In particular, long noncoding RNAs (lncRNAs) …

Background In the study of transposable elements (TEs), the generation of a high
confidence set of consensus sequences that represent the diversity of TEs found in a given …

Our knowledge of the structure and composition of genomes is rapidly progressing in pace
with their sequencing. The emerging data show that a significant portion of eukaryotic …

The role of RNA polymerase (Pol) III in eukaryotic transcription is commonly thought of as
being restricted to a small set of highly expressed, housekeeping non–protein-coding (nc) …

Retrotransposons, mainly LINEs, SINEs, and endogenous retroviruses, make up roughly
40% of the mammalian genome and have played an important role in genome evolution …

Noncoding RNAs (ncRNAs) have recently been discovered to regulate mRNA transcription
in trans, a role traditionally reserved for proteins. The breadth of ncRNAs as transacting …

Recent comprehensive sequence analysis of the maize genome now permits detailed
discovery and description of all transposable elements (TEs) in this complex nuclear …

Transposable elements (TEs) have shared an exceptionally long coexistence with their host
organisms and have come to occupy a significant fraction of eukaryotic genomes. The bulk …

Up to 10% of the mouse genome is comprised of endogenous retrovirus (ERV) sequences,
and most represent the remains of ancient germ line infections. Our knowledge of the three …