[HTML][HTML] Leveraging knowledge of HDLs major protein ApoA1: Structure, function, mutations, and potential therapeutics

AS Bhale, K Venkataraman - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Abstract Apolipoprotein A1 (ApoA1) is a member of the Apolipoprotein family of proteins. It's
a vital protein that helps in the production of high-density lipoprotein (HDL) particles, which …

[HTML][HTML] The ketogenic diet and cardiovascular diseases

D Dyńka, K Kowalcze, A Charuta, A Paziewska - Nutrients, 2023 - mdpi.com
The most common and increasing causes of death worldwide are cardiovascular diseases
(CVD). Taking into account the fact that diet is a key factor, it is worth exploring this aspect of …

[HTML][HTML] Significance of sphingosine-1-phosphate in cardiovascular physiology and pathology

E Józefczuk, TJ Guzik, M Siedlinski - Pharmacological research, 2020 - Elsevier
Abstract Sphingosine-1-phosphate (S1P) is a signaling lipid, synthetized by sphingosine
kinases (SPHK1 and SPHK2), that affects cardiovascular function in various ways. S1P …

Effects of the treatment with flavonoids on metabolic syndrome components in humans: A systematic review focusing on mechanisms of action

HJCB Gouveia, MV Urquiza-Martínez… - International journal of …, 2022 - mdpi.com
Diets high in bioactive compounds, such as polyphenols, have been used to mitigate
metabolic syndrome (MetS). Polyphenols are a large group of naturally occurring bioactive …

Ginsenoside Rc ameliorated atherosclerosis via regulating gut microbiota and fecal metabolites

B Xie, X Zu, Z Wang, X Xu, G Liu, R Liu - Frontiers in Pharmacology, 2022 - frontiersin.org
Atherosclerosis (AS) and the accompanied cardiovascular diseases (CVDs) were the
leading cause of death worldwide. Recently, the association between CVDs, gut microbiota …

Increased expression of meteorin-like hormone in type 2 diabetes and obesity and its association with irisin

I AlKhairi, P Cherian, M Abu-Farha, AA Madhoun… - Cells, 2019 - mdpi.com
Type 2 diabetes (T2D) is a growing pandemic associated with metabolic dysregulation and
chronic inflammation. Meteorin-like hormone (METRNL) is an adipomyokine that is linked to …

Connection between periodontitis-induced low-grade endotoxemia and systemic diseases: neutrophils as protagonists and targets

L Vitkov, LE Muñoz, J Knopf, C Schauer… - International journal of …, 2021 - mdpi.com
Periodontitis is considered a promoter of many systemic diseases, but the signaling
pathways of this interconnection remain elusive. Recently, it became evident that certain …

High-density lipoproteins (HDL): novel function and therapeutic applications

M Darabi, A Kontush - Biochimica et Biophysica Acta (BBA)-Molecular and …, 2022 - Elsevier
The failure of high-density lipoprotein (HDL)-raising agents to reduce cardiovascular
disease (CVD) together with recent findings of increased cardiovascular mortality in subjects …

Resveratrol butyrate esters inhibit obesity caused by perinatal exposure to bisphenol A in female offspring rats

MK Shih, YL Tain, YW Chen, WH Hsu, YT Yeh… - Molecules, 2021 - mdpi.com
Resveratrol butyrate esters (RBE) are derivatives of resveratrol (RSV) and butyric acid and
exhibit biological activity similar to that of RSV but with higher bioavailability. The aim of this …

Short-term treatment with high dose liraglutide improves lipid and lipoprotein profile and changes hormonal mediators of lipid metabolism in obese patients with no …

N Peradze, OM Farr, N Perakakis, I Lázaro… - Cardiovascular …, 2019 - Springer
Objective Long-term treatment with up to 1.8 mg liraglutide improves cardiovascular and all-
cause mortality in patients with type 2 diabetes at high risk for cardiovascular disease (CVD) …