Quantitative analysis of thin-section CT of the chest has a growing role in the clinical
evaluation and management of diffuse lung diseases. This heterogeneous group includes …

The small airways are defined as those less than 2 mm in diameter. They are a major site of
pathology in many lung diseases, not least chronic obstructive pulmonary disease (COPD) …

The purpose of this statement is to describe and define the phenotypic abnormalities that
can be identified on visual and quantitative evaluation of computed tomographic (CT) …

Importance Airflow obstruction on spirometry is universally used to define chronic obstructive
pulmonary disease (COPD), and current or former smokers without airflow obstruction may …

Multidetector row computed tomography (MDCT) is increasingly taking a central role in
identifying subphenotypes within chronic obstructive pulmonary disease (COPD), asthma …

Purpose To determine whether visually assessed patterns of emphysema at CT might
provide a simple assessment of mortality risk among cigarette smokers. Materials and …

Rationale: Studies of excised lungs show that significant airway attrition in the “quiet” zone
occurs early in chronic obstructive pulmonary disease (COPD). Objectives: To determine if …

The Genetic Epidemiology of Chronic Obstructive Pulmonary Disease (COPDGene) study,
which began in 2007, is an ongoing multicenter observational cohort study of more than …

Chronic obstructive pulmonary disease (COPD) exhibits significant heterogeneity in its
clinical presentation and rate of disease progression among affected individuals, owing at …

Quantitative computed tomography is being increasingly used to quantify the features of
chronic obstructive pulmonary disease, specifically emphysema, air trapping, and airway …