Poloxamer: A versatile tri-block copolymer for biomedical applications

P Zarrintaj, JD Ramsey, A Samadi, Z Atoufi, MK Yazdi… - Acta biomaterialia, 2020 - Elsevier
Poloxamers, also called Pluronic, belong to a unique class of synthetic tri-block copolymers
containing central hydrophobic chains of poly (propylene oxide) sandwiched between two …

Cancer nanotechnology: a new revolution for cancer diagnosis and therapy

VK Chaturvedi, A Singh, VK Singh… - Current drug …, 2019 - ingentaconnect.com
Background: Nanotechnology is gaining significant attention worldwide for cancer treatment.
Nanobiotechnology encourages the combination of diagnostics with therapeutics, which is a …

Biocompatibility and safety of PLA and its copolymers

Y Ramot, M Haim-Zada, AJ Domb, A Nyska - Advanced drug delivery …, 2016 - Elsevier
PLA and its copolymers are commonly used for a wide variety of applications. While they are
considered to be biocompatible, side effects resulting from their implantation have been …

Polymeric mixed micelles as nanomedicines: Achievements and perspectives

M Cagel, FC Tesan, E Bernabeu, MJ Salgueiro… - European Journal of …, 2017 - Elsevier
During the past few decades, polymeric micelles have raised special attention as novel
nano-sized drug delivery systems for optimizing the treatment and diagnosis of numerous …

Oral empagliflozin-loaded tri-layer core-sheath fibers fabricated using tri-axial electrospinning: enhanced in vitro and in vivo antidiabetic performance

E Guler, AN Hazar-Yavuz, E Tatar, MM Haidari… - International journal of …, 2023 - Elsevier
Empagliflozin (EM) was successfully loaded in polycaprolactone/poly (L-lactic
acid)/polymethyl methacrylate (PCL/PLA/PMMA) fibers. In the rat β-cell line (BRIN-BD11) …

Nanocarrier for poorly water-soluble anticancer drugs—barriers of translation and solutions

M Narvekar, HY Xue, JY Eoh, HL Wong - Aaps Pharmscitech, 2014 - Springer
Many existing chemotherapeutic drugs, repurposed drugs and newly developed small-
molecule anticancer compounds have high lipophilicity and low water-solubility. Currently …

Tumor microenvironment targeted nanotherapy

C Fernandes, D Suares, MC Yergeri - Frontiers in pharmacology, 2018 - frontiersin.org
Recent developments in nanotechnology have brought new approaches to cancer
diagnosis and therapy. While enhanced permeability and retention effect promotes nano …

Advanced imaging techniques for tracking drug dynamics at the subcellular level

C Zhang, Z Tian, R Chen, F Rowan, K Qiu… - Advanced Drug Delivery …, 2023 - Elsevier
Optical microscopes are an important imaging tool that have effectively advanced the
development of modern biomedicine. In recent years, super-resolution microscopy (SRM) …

Polymeric nanomicelles of curcumin: Potential applications in cancer

L Farhoudi, P Kesharwani, M Majeed… - International Journal of …, 2022 - Elsevier
Natural compounds, primarily derived from plants, have been isolated and evaluated as
alternative and complementary treatments for cancer. Curcumin has been proven to be …

Self-assembled nanoparticles based on hyaluronic acid-ceramide (HA-CE) and Pluronic® for tumor-targeted delivery of docetaxel

HJ Cho, HY Yoon, H Koo, SH Ko, JS Shim, JH Lee… - Biomaterials, 2011 - Elsevier
Hyaluronic acid-ceramide (HA-CE)-based self-assembled nanoparticles were developed for
intravenous docetaxel (DCT) delivery. In this study, physicochemical properties, cellular …