Studies in neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease
and Amyotrophic lateral sclerosis, Huntington's disease, and so on, have suggested that …

The novel Coronavirus disease 2019 (COVID-19) is caused by SARS-CoV-2, which is the
causative agent of a potentially fatal disease that is of great global public health concern …

Advanced glycation end products (AGEs) are potentially harmful and heterogeneous
molecules derived from nonenzymatic glycation. The pathological implications of AGEs are …

Accumulation of advanced glycation end products (AGEs) on nucleotides, lipids, and
peptides/proteins are an inevitable component of the aging process in all eukaryotic …

Parkinson's disease (PD) is a complex, chronic and progressive neurodegenerative
disease. While the etiology of PD is likely multifactorial, the protein α-synuclein is a central …

'Inflammaging'refers to the chronic, low-grade inflammation that characterizes aging.
Inflammaging is macrophage centered, involves several tissues and organs, including the …

The receptor for advanced glycation end products (RAGE) is a non-specific multi-ligand
pattern recognition receptor capable of binding to a range of structurally diverse ligands …

Abstract α-Synuclein is strongly linked to Parkinson's disease but the molecular targets for its
toxicity are not fully clear. However, many neuronal functions damaged in Parkinson's …

Abnormal aggregation of proteins into filamentous aggregates commonly associates with
many diseases, such as Alzheimer's disease, Parkinson's disease and type-2 diabetes …

Alpha-synuclein is a small neuronal protein that is closely associated with the etiology of
Parkinson's disease. Mutations in and alterations in expression levels of alpha-synuclein …