3-Nitrotyrosine: A biomarker of nitrogen free radical species modified proteins in systemic autoimmunogenic conditions

H Ahsan - Human immunology, 2013 - Elsevier
The free radical-mediated damage to proteins results in the modification of amino acid
residues, cross-linking of side chains and fragmentation. l-Tyrosine and protein bound …

Peroxynitrite: cellular pathology and implications in autoimmunity

R Ahmad, A Hussain, H Ahsan - Journal of Immunoassay and …, 2019 - Taylor & Francis
In inflamed tissues, the reaction of nitric oxide and superoxide leads to the formation of an
extremely reactive peroxynitrite (ONOO−), which is a well known oxidizing and nitrating …

Markers of oxidative and nitrosative stress in systemic lupus erythematosus: correlation with disease activity

G Wang, SS Pierangeli, E Papalardo… - Arthritis & …, 2010 - Wiley Online Library
Objective Free radical–mediated reactions have been implicated as contributors in a
number of autoimmune diseases, including systemic lupus erythematosus (SLE). However …

A fluorophore anchored MOF for fast and sensitive sensing of Cu (ii) and 3-nitrotyrosine in a physiological medium

S Mukherjee, K Sarkar, S Biswas - Dalton Transactions, 2023 - pubs.rsc.org
We report the solvothermal synthesis of a dansyl anchored hafnium based fluorescent metal–
organic framework (MOF) having the formula [Hf6O4 (OH) 4 (L) 6]· H2O· 6DMF (H2L= 2-((5 …

3-Nitrotyrosine quantification methods: Current concepts and future challenges

D Teixeira, R Fernandes, C Prudêncio, M Vieira - Biochimie, 2016 - Elsevier
Abstract Background Measurement of 3-nitrotyrosine (3-NT) in biological samples can be
used as a biomarker of nitrosative stress, since it is very stable and suitable for analysis …

[HTML][HTML] Oxidative post-translational modifications and their involvement in the pathogenesis of autoimmune diseases

BJ Ryan, A Nissim, PG Winyard - Redox biology, 2014 - Elsevier
Tissue inflammation results in the production of numerous reactive oxygen, nitrogen and
chlorine species, in addition to the products of lipid and sugar oxidation. Some of these …

The emerging role of autoimmunity in myalgic encephalomyelitis/chronic fatigue syndrome (ME/cfs)

G Morris, M Berk, P Galecki, M Maes - Molecular neurobiology, 2014 - Springer
Abstract The World Health Organization classifies myalgic encephalomyelitis/chronic fatigue
syndrome (ME/cfs) as a nervous system disease. Together with other diseases under the …

The key culprit in the pathogenesis of systemic lupus erythematosus: aberrant DNA methylation

H Wu, M Zhao, L Tan, Q Lu - Autoimmunity reviews, 2016 - Elsevier
Systemic lupus erythematosus (SLE) is an autoimmune disease with multiple organ
involvement. It is characterized by abundant autoantibodies that form immune complex with …

Advancements in the analytical quantification of nitroxidative stress biomarker 3-nitrotyrosine in biological matrices

M Bandookwala, D Thakkar… - Critical Reviews in …, 2020 - Taylor & Francis
Dysfunction of the antioxidant system or mutations in the gene may result in the elevated
production of certain biomarkers. 3-nitrotyrosine (3-NT) is one such promising biomarker of …

MXene nanosheet-derived N, S-codoped graphene quantum dots for ultrasensitive and selective detection of 3-nitro-l-tyrosine in human serum

NTN Anh, TV Huynh, TKA Nguyen, R Doong - Analytica Chimica Acta, 2024 - Elsevier
Nitro-l-tyrosine (3NT) is an oxidative stress metabolite associated with neurodegenerative
diseases such as Parkinson's disease and rheumatoid arthritis. In this study, the N, S-co …