The development of implantable neuroelectrodes is advancing rapidly as these tools are
becoming increasingly ubiquitous in clinical practice, especially for the treatment of …

Traffic accidents and falling objects are responsible for most spinal cord injuries (SCIs). SCI
is characterized by high disability and tends to occur among the young, seriously affecting …

We developed a nanoparticle base layer technology capable of maintaining the bioactivity of
protein-based neural probe coating intended to improve neural recording quality. When …

In the human body, cells in a tissue are exposed to signals derived from their specific
extracellular matrix (ECM), such as architectural structure, mechanical properties, and …

Following spinal cord injury, astrocytes at the site of injury become reactive and exhibit a
neurotoxic (A1) phenotype, which leads to neuronal death. In addition, the glial scar, which …

Electrospinning is a fabrication technique used to produce nano-or micro-diameter fibers to
generate biocompatible, biodegradable scaffolds for tissue engineering applications …

Skin is designed to protect various tissues, and because it is the largest and first human
bodily organ to sustain damage, it has an incredible ability to regenerate. On account of …

Three aligned, electrospun fiber scaffolds with unique surface features were created from
poly-L-lactic acid (PLLA). Fibers without surface nanotopography (smooth fibers), fibers with …

Surface topographies at micro-and nanoscales can influence different cellular behavior,
such as their growth rate and directionality. While different techniques have been …

It is important for the functional recovery of defective nerves to construct a suitable
microenvironment for nerve regeneration by optimizing the topological structure and …