Herbicide resistant (HR) weeds are of major concern in modern agriculture. This situation is
exacerbated by the massive adoption of herbicide-based technologies along with the …

Genetic biocontrol aims to suppress or modify populations of species to protect public
health, agriculture, and biodiversity. Advancements in genome engineering technologies …

Abstract Cas9/gRNA-mediated gene-drive systems have advanced development of genetic
technologies for controlling vector-borne pathogen transmission. These technologies …

A gene drive biases the transmission of one of the two copies of a gene such that it is
inherited more frequently than by random segregation. Highly efficient gene drive systems …

Gene drives have enormous potential for the control of insect populations of medical and
agricultural relevance. By preferentially biasing their own inheritance, gene drives can …

A functioning gene drive system could fundamentally change our strategies for the control of
vector-borne diseases by facilitating rapid dissemination of transgenes that prevent …

CRISPR/Cas9 gene drive (CGD) promises to be a highly adaptable approach for spreading
genetically engineered alleles throughout a species, even if those alleles impair …

CRISPR homing gene drives can convert heterozygous cells with one copy of the drive
allele into homozygotes, thereby enabling super-Mendelian inheritance. Such a mechanism …

If they are able to spread in wild populations, CRISPR-based gene-drive elements would
provide new ways to address ecological problems by altering the traits of wild organisms …

Interest in developing gene drive systems to control invasive species is growing, with New
Zealand reportedly considering the nascent technology as a way to locally eliminate the …