Frontotemporal lobar degeneration
Frontotemporal lobar degeneration (FTLD) is one of the most common causes of early-onset
dementia and presents with early social–emotional–behavioural and/or language changes …
dementia and presents with early social–emotional–behavioural and/or language changes …
Iron in neurodegeneration–cause or consequence?
A Ndayisaba, C Kaindlstorfer… - Frontiers in neuroscience, 2019 - frontiersin.org
Iron dyshomeostasis can cause neuronal damage to iron-sensitive brain regions.
Neurodegeneration with brain iron accumulation reflects a group of disorders caused by iron …
Neurodegeneration with brain iron accumulation reflects a group of disorders caused by iron …
[HTML][HTML] Post mortem mapping of connectional anatomy for the validation of diffusion MRI
Diffusion MRI (dMRI) is a unique tool for the study of brain circuitry, as it allows us to image
both the macroscopic trajectories and the microstructural properties of axon bundles in vivo …
both the macroscopic trajectories and the microstructural properties of axon bundles in vivo …
An open resource combining multi-contrast MRI and microscopy in the macaque brain
Understanding brain structure and function often requires combining data across different
modalities and scales to link microscale cellular structures to macroscale features of whole …
modalities and scales to link microscale cellular structures to macroscale features of whole …
Biomarkers in amyotrophic lateral sclerosis: current status and future prospects
Disease heterogeneity in amyotrophic lateral sclerosis poses a substantial challenge in drug
development. Categorization based on clinical features alone can help us predict the …
development. Categorization based on clinical features alone can help us predict the …
Presymptomatic spinal cord pathology in c9orf72 mutation carriers: A longitudinal neuroimaging study
Objective C9orf72 hexanucleotide repeats expansions account for almost half of familial
amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) cases. Recent …
amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) cases. Recent …
[HTML][HTML] Ex vivo MRI and histopathology detect novel iron-rich cortical inflammation in frontotemporal lobar degeneration with tau versus TDP-43 pathology
Frontotemporal lobar degeneration (FTLD) is a heterogeneous spectrum of age-associated
neurodegenerative diseases that include two main pathologic categories of tau (FTLD-Tau) …
neurodegenerative diseases that include two main pathologic categories of tau (FTLD-Tau) …
The Digital Brain Bank, an open access platform for post-mortem imaging datasets
BC Tendler, T Hanayik, O Ansorge… - Elife, 2022 - elifesciences.org
Post-mortem magnetic resonance imaging (MRI) provides the opportunity to acquire high-
resolution datasets to investigate neuroanatomy and validate the origins of image contrast …
resolution datasets to investigate neuroanatomy and validate the origins of image contrast …
[HTML][HTML] Methods for quantitative susceptibility and R2* mapping in whole post-mortem brains at 7T applied to amyotrophic lateral sclerosis
Susceptibility weighted magnetic resonance imaging (MRI) is sensitive to the local
concentration of iron and myelin. Here, we describe a robust image processing pipeline for …
concentration of iron and myelin. Here, we describe a robust image processing pipeline for …
Structural magnetic resonance imaging findings and histopathological correlations in motor neuron diseases—A systematic review and meta-analysis
C Zejlon, D Nakhostin, S Winklhofer, A Pangalu… - Frontiers in …, 2022 - frontiersin.org
Objectives The lack of systematic evidence on neuroimaging findings in motor neuron
diseases (MND) hampers the diagnostic utility of magnetic resonance imaging (MRI). Thus …
diseases (MND) hampers the diagnostic utility of magnetic resonance imaging (MRI). Thus …