Global burden of hepatitis B virus: current status, missed opportunities and a call for action

YC Hsu, DQ Huang, MH Nguyen - Nature Reviews Gastroenterology & …, 2023 - nature.com
Chronic hepatitis B virus (HBV) infection affects about 296 million people worldwide and is
the leading aetiology of cirrhosis and liver cancer globally. Major medical complications also …

Changing epidemiology of hepatocellular carcinoma in Asia

C Zhang, Y Cheng, S Zhang, J Fan, Q Gao - Liver International, 2022 - Wiley Online Library
Liver cancer is the fifth most common cancer and the second leading cause of malignant
death in Asia, and Asia reports 72.5% of the world's cases in 2020. As the most common …

The Asian Pacific Association for the Study of the Liver clinical practice guidelines for the diagnosis and management of metabolic associated fatty liver disease

M Eslam, SK Sarin, VWS Wong, JG Fan… - Hepatology …, 2020 - Springer
Metabolic associated fatty liver disease (MAFLD) is the principal worldwide cause of liver
disease and affects nearly a quarter of the global population. The objective of this work was …

Updated epidemiology of gastrointestinal cancers in East Asia

J Huang, DE Lucero-Prisno III, L Zhang, W Xu… - Nature Reviews …, 2023 - nature.com
Globally, gastrointestinal cancers represent more than one-fourth of all cancer incidence
and one-third of cancer-related mortality. Although there has been much progress in …

Changes in the global burden of chronic liver diseases from 2012 to 2017: the growing impact of NAFLD

JM Paik, P Golabi, Y Younossi, A Mishra… - Hepatology, 2020 - journals.lww.com
Conclusions Our findings indicate that LINC00665 is involved in the NF‐κB signaling
activation in HCC cells and that the inflammatory LINC00665/PKR/NF‐κB loop plays …

Gut microbiome, liver immunology, and liver diseases

R Wang, R Tang, B Li, X Ma, B Schnabl… - Cellular & molecular …, 2021 - nature.com
The gut microbiota is a complex and plastic consortium of microorganisms that are intricately
connected with human physiology. The liver is a central immunological organ that is …

Contemporary epidemiology of chronic liver disease and cirrhosis

AM Moon, AG Singal, EB Tapper - Clinical Gastroenterology and …, 2020 - Elsevier
Background & Aims Accurate estimates for the contemporary burden of chronic liver disease
(CLD) are vital for setting clinical, research, and policy priorities. We aimed to review the …

[HTML][HTML] Epidemiology of non-alcoholic and alcoholic fatty liver diseases

S Mitra, A De, A Chowdhury - Translational gastroenterology and …, 2020 - ncbi.nlm.nih.gov
Liver diseases are fast emerging as global health priorities. Fatty liver is described in the
setting of non-alcoholic fatty liver disease (NAFLD) as well as alcoholic liver disease (ALD) …

Non-alcoholic fatty liver disease–a global public health perspective

ZM Younossi - Journal of hepatology, 2019 - Elsevier
As the epidemics of obesity and type 2 diabetes mellitus increase worldwide, the prevalence
of non-alcoholic fatty liver disease (NAFLD) is increasing proportionately. The subtype of …

[PDF][PDF] Unexpected rapid increase in the burden of NAFLD in China from 2008 to 2018: a systematic review and meta‐analysis

F Zhou, J Zhou, W Wang, XJ Zhang, YX Ji… - …, 2019 - Wiley Online Library
With rapid lifestyle transitions, the increasing burden of nonalcoholic fatty liver disease
(NAFLD) in China has emerged as a major public health issue. To obtain a comprehensive …