Cells release nanometer-scale, lipid bilayer-enclosed biomolecular packages (extracellular vesicles; EVs) into their surrounding environment. EVs are hypothesized to be intercellular …
The therapeutic benefits of mesenchymal stromal cell (MSC) transplantation are attributed to their secreted factors, including extracellular vesicles (EVs) and soluble factors. The …
D Tsiapalis, L O'Driscoll - Cells, 2020 - mdpi.com
Mesenchymal stem cells (MSCs) are being extensively investigated for their potential in tissue engineering and regenerative medicine. However, recent evidence suggests that the …
B Claridge, J Lozano, QH Poh… - Frontiers in Cell and …, 2021 - frontiersin.org
Extracellular vesicles (EVs) hold great promise as therapeutic modalities due to their endogenous characteristics, however, further bioengineering refinement is required to …
A Trzyna, A Banaś-Ząbczyk - Biomolecules, 2021 - mdpi.com
Adipose-derived stem cells (ASCs) secrete many cytokines, proteins, growth factors, and extracellular vesicles with beneficial outcomes that can be used in regenerative medicine. It …
S Varderidou-Minasian, MJ Lorenowicz - Theranostics, 2020 - ncbi.nlm.nih.gov
Mesenchymal stem/stromal cells (MSCs) are important players in tissue homeostasis and regeneration owing to their immunomodulatory potential and release of trophic factors that …
A Nagelkerke, M Ojansivu, L van der Koog… - Advanced drug delivery …, 2021 - Elsevier
Extracellular vesicles (EVs) are biological nanoparticles naturally secreted by cells, acting as delivery vehicles for molecular messages. During the last decade, EVs have been …
R Stavely, K Nurgali - Stem Cells Translational Medicine, 2020 - academic.oup.com
Mesenchymal stem cells (multipotent stromal cells; MSCs) have been under investigation for the treatment of diverse diseases, with many promising outcomes achieved in animal …
V Planat-Benard, A Varin, L Casteilla - Frontiers in immunology, 2021 - frontiersin.org
Mesenchymal stromal cells (MSCs) are currently widely used in cell based therapy regarding to their remarkable efficacy in controlling the inflammatory status in patients …