Role of the gut–brain axis in energy and glucose metabolism
HR Wachsmuth, SN Weninger, FA Duca - Experimental & molecular …, 2022 - nature.com
The gastrointestinal tract plays a role in the development and treatment of metabolic
diseases. During a meal, the gut provides crucial information to the brain regarding …
diseases. During a meal, the gut provides crucial information to the brain regarding …
Neuroendocrine peptides of the gut and their role in the regulation of food intake
MA Schalla, Y Taché, A Stengel - Comprehensive Physiology, 2011 - Wiley Online Library
The regulation of food intake encompasses complex interplays between the gut and the
brain. Among them, the gastrointestinal tract releases different peptides that communicate …
brain. Among them, the gastrointestinal tract releases different peptides that communicate …
Infusion of exogenous cholecystokinin-8, gastrin releasing peptide-29 and their combination reduce body weight in diet-induced obese male rats
TR Mhalhal, MC Washington, K Newman, JC Heath… - Appetite, 2017 - Elsevier
We hypothesized that exogenous gastrin releasing peptide-29 (GRP-29), cholecystokinin-8
(CCK-8) and their combination reduce body weight (BW). To test this hypothesis, BW was …
(CCK-8) and their combination reduce body weight (BW). To test this hypothesis, BW was …
Exogenous glucagon-like peptide-1 reduces body weight and cholecystokinin-8 enhances this reduction in diet-induced obese male rats
TR Mhalhal, MC Washington, K Newman, JC Heath… - Physiology & …, 2017 - Elsevier
The sites of action regulating meal size (MS) and intermeal interval (IMI) length by glucagon
like peptide-1 (7–36)(GLP-1 (7–36)) and cholecystokinin-8 (CCK-8) reside in the areas …
like peptide-1 (7–36)(GLP-1 (7–36)) and cholecystokinin-8 (CCK-8) reside in the areas …
Combined gastrin releasing peptide-29 and glucagon like peptide-1 reduce body weight more than each individual peptide in diet-induced obese male rats
TR Mhalhal, MC Washington, KD Newman, JC Heath… - Neuropeptides, 2018 - Elsevier
To test the hypothesis that gastrin releasing peptide-29 (GRP-29) combined with glucagon
like peptide-1 (7–36)(GLP-1 (7–36)) reduce body weight (BW) more than each of the …
like peptide-1 (7–36)(GLP-1 (7–36)) reduce body weight (BW) more than each of the …
Non-sulfated cholecystokinin-8 reduces meal size and prolongs the intermeal interval in male Sprague Dawley rats
AI Dafalla, TR Mhalhal, MC Washington, S Spann… - Neuropeptides, 2019 - Elsevier
The current study measured seven feeding responses by non-sulfated cholecystokinin-8
(NS CCK-8) in freely fed adult male Sprague Dawley rats. The peptide (0, 0.5, 1, 3, 5 and 10 …
(NS CCK-8) in freely fed adult male Sprague Dawley rats. The peptide (0, 0.5, 1, 3, 5 and 10 …
Effect of vagotomy and sympathectomy on the feeding responses evoked by intra-aortic cholecystokinin-8 in adult male sprague dawley rats
TR Mhalhal, MC Washington, JC Heath… - Endocrine …, 2021 - Taylor & Francis
The vagus nerve and the celiaco-mesenteric ganglia (CMG) are required for reduction of
meal size (MS) and prolongation of the intermeal interval (IMI) by intraperitoneal (ip) sulfated …
meal size (MS) and prolongation of the intermeal interval (IMI) by intraperitoneal (ip) sulfated …
Non-sulfated cholecystokinin-8 increases enteric and hindbrain Fos-like immunoreactivity in male Sprague Dawley rats
AI Dafalla, TR Mhalhal, K Hiscocks, J Heath, AI Sayegh - Brain research, 2019 - Elsevier
Recently, we reported that non-sulfated cholecystokinin-8 (NS CCK-8) reduces food intake
by cholecystokinin-B receptors (CCK-BR). To examine a possible site of action for this …
by cholecystokinin-B receptors (CCK-BR). To examine a possible site of action for this …
Gut peptides: gastrin releasing peptide, cholecystokinin, and glucagon-like peptide-1 in the regulation of food intake and satiety
TR Mhalhal, YJ Mohammed, JASD Alahme… - 2022 - cabidigitallibrary.org
Obesity is an imbalance between energy intake and energy expenditure. This imbalance is
manifested clinically by accumulation of fat primarily in the abdomen, in cases of males, and …
manifested clinically by accumulation of fat primarily in the abdomen, in cases of males, and …
Peptide Tyrosine Tyrosine 3-36 Reduces Meal Size and Activates the Enteric Neurons in Male Sprague–Dawley Rats
KD Newman, TR Mhalhal, MC Washington… - Digestive Diseases and …, 2017 - Springer
Abstract Background Peptide tyrosine tyrosine 3-36 (peptide YY 3-36 or PYY 3-36) reduces
food intake by unknown site (s). Aim To test the hypothesis that the gastrointestinal tract …
food intake by unknown site (s). Aim To test the hypothesis that the gastrointestinal tract …