Background Tuberculosis (TB) is the world's leading infectious cause of death.
Extrapulmonary TB accounts for 15% of TB cases, but the proportion is increasing, and over …

Background Every year, an estimated one million children and young adolescents become
ill with tuberculosis, and around 226,000 of those children die. Xpert MTB/RIF Ultra (Xpert …

Background Xpert MTB/RIF Ultra (Xpert Ultra) and Xpert MTB/RIF are World Health
Organization (WHO)‐recommended rapid nucleic acid amplification tests (NAATs) widely …

Background Every year, at least one million children become ill with tuberculosis and
around 200,000 children die. Xpert MTB/RIF and Xpert Ultra are World Health Organization …

Importance Criterion-standard specimens for tuberculosis diagnosis in young children,
gastric aspirate (GA) and induced sputum, are invasive and rarely collected in resource …

Objectives The WHO currently recommends stool testing using GeneXpert MTB/Rif (Xpert)
for the diagnosis of paediatric tuberculosis (TB). The simple one-step (SOS) stool method …

Background Diagnosis of intrathoracic tuberculosis (ITB) is limited in children partly by their
difficulty to produce sputum specimen. Objective To systematically review the detection …

Background Diagnosis of TB in children is challenging, and is largely based on positive
history of contact with a TB case, clinical and radiological findings, often without …

Abstract Background As access to Xpert expands in high TB-burden settings, its
performance against clinically diagnosed TB as a reference standard provides important …

SETTING: Médecins Sans Frontières (MSF) clinic in Mumbai, India. OBJECTIVE: To
determine the final treatment outcomes, culture conversion and adverse events (AEs) during …