(Nano) platforms in breast cancer therapy: drug/gene delivery, advanced nanocarriers and immunotherapy

M Ashrafizadeh, A Zarrabi, A Bigham… - Medicinal Research …, 2023 - Wiley Online Library
Breast cancer is the most malignant tumor in women, and there is no absolute cure for it.
Although treatment modalities including surgery, chemotherapy, and radiotherapy are …

Interplay between LncRNAs and microRNAs in breast cancer

H Schwarzenbach, PB Gahan - International journal of molecular …, 2023 - mdpi.com
(1) Although long noncoding RNAs (lncRNAs) are known to be precursors of microRNAs
(miRNAs), they frequently act as competing endogoneous RNAs (ceRNAs), yet still their …

[HTML][HTML] A novel axis of circKIF4A-miR-637-STAT3 promotes brain metastasis in triple-negative breast cancer

S Wu, J Lu, H Zhu, F Wu, Y Mo, L Xie, C Song, L Liu… - Cancer Letters, 2024 - Elsevier
Among patients with triple-negative breast cancer (TNBC), distant metastasis is the leading
cause of death. Our previous studies have shown that TNBC progression is greatly …

Non-coding RNAs and macrophage interaction in tumor progression

M Entezari, M Sadrkhanloo, M Rashidi, SE Asnaf… - Critical reviews in …, 2022 - Elsevier
The macrophages are abundantly found in TME and their M2 polarization is in favor of tumor
malignancy. On the other hand, non-coding RNAs (ncRNAs) can modulate macrophage …

[HTML][HTML] LncRNA MNX1-AS1 sustains inactivation of Hippo pathway through a positive feedback loop with USP16/IGF2BP3 axis in gallbladder cancer

S Liu, H Li, Y Zhu, X Ma, Z Shao, Z Yang, C Cai, Z Wu… - Cancer Letters, 2022 - Elsevier
The long non-coding RNAs (lncRNAs) have been implicated in multiple human cancers,
which may offer great potential as putative targets for cancer diagnosis and treatment …

lncRNA-microRNA axis in cancer drug resistance: particular focus on signaling pathways

RO Saleh, MTS Al-Ouqaili, E Ali, S Alhajlah… - Medical Oncology, 2024 - Springer
Cancer drug resistance remains a formidable challenge in modern oncology, necessitating
innovative therapeutic strategies. The convergence of intricate regulatory networks involving …

PI3K/Akt signalling pathway-associated long noncoding RNA signature predicts the prognosis of laryngeal cancer patients

Q Nie, H Cao, JW Yang, T Liu, B Wang - Scientific Reports, 2023 - nature.com
Abstract The PI3K/Akt signalling pathway is associated with the occurrence and
development of tumours and significantly affects the prognosis of patients. We established a …

[HTML][HTML] The role of lncRNAs and exosomal lncRNAs in cancer metastasis

Y Zhang, L Zhao, Y Bi, J Zhao, C Gao, X Si… - Biomedicine & …, 2023 - Elsevier
Tumor metastasis is the main reason for cancer-related death, but there is still a lack of
effective therapeutic to inhibit tumor metastasis. Therefore, the discovery and study of new …

Functional interplay between long non-coding RNAs and Breast CSCs

BM Hussen, RK Kheder, ST Abdullah, HJ Hidayat… - Cancer Cell …, 2022 - Springer
Breast cancer (BC) represents aggressive cancer affecting most women's lives globally.
Metastasis and recurrence are the two most common factors in a breast cancer patient's …

The expanding role of cancer stem cell marker ALDH1A3 in cancer and beyond

ME McLean, MR MacLean, HF Cahill, RP Arun… - Cancers, 2023 - mdpi.com
Simple Summary Aldehyde dehydrogenase 1A3 (ALDH1A3) is the primary cause of the high
ALDH activity associated with cancer stem cell (CSC) populations in multiple cancers and its …