Neuronal regulation of energy homeostasis: beyond the hypothalamus and feeding

MJ Waterson, TL Horvath - Cell metabolism, 2015 - cell.com
The essential role of the brain in maintaining energy homeostasis has motivated the drive to
define the neural circuitry that integrates external and internal stimuli to enact appropriate …

Central neural regulation of brown adipose tissue thermogenesis and energy expenditure

SF Morrison, CJ Madden, D Tupone - Cell metabolism, 2014 - cell.com
Thermogenesis, the production of heat energy, is the specific, neurally regulated, metabolic
function of brown adipose tissue (BAT) and contributes to the maintenance of body …

Gating of social reward by oxytocin in the ventral tegmental area

LW Hung, S Neuner, JS Polepalli, KT Beier, M Wright… - Science, 2017 - science.org
The reward generated by social interactions is critical for promoting prosocial behaviors.
Here we present evidence that oxytocin (OXT) release in the ventral tegmental area (VTA), a …

[HTML][HTML] Social touch-like tactile stimulation activates a tachykinin 1-oxytocin pathway to promote social interactions

H Yu, W Miao, E Ji, S Huang, S Jin, X Zhu, MZ Liu… - Neuron, 2022 - cell.com
It is well known that affective and pleasant touch promotes individual well-being and
facilitates affiliative social communication, although the neural circuit that mediates this …

Oxytocin enables maternal behaviour by balancing cortical inhibition

BJ Marlin, M Mitre, JA D'amour, MV Chao, RC Froemke - Nature, 2015 - nature.com
Oxytocin is important for social interactions and maternal behaviour. However, little is known
about when, where and how oxytocin modulates neural circuits to improve social cognition …

Oxytocin-dependent reopening of a social reward learning critical period with MDMA

R Nardou, EM Lewis, R Rothhaas, R Xu, A Yang… - Nature, 2019 - nature.com
A critical period is a developmental epoch during which the nervous system is expressly
sensitive to specific environmental stimuli that are required for proper circuit organization …

An excitatory paraventricular nucleus to AgRP neuron circuit that drives hunger

MJ Krashes, BP Shah, JC Madara, DP Olson… - Nature, 2014 - nature.com
Hunger is a hard-wired motivational state essential for survival. Agouti-related peptide
(AgRP)-expressing neurons in the arcuate nucleus (ARC) at the base of the hypothalamus …

A neural basis for melanocortin-4 receptor–regulated appetite

AS Garfield, C Li, JC Madara, BP Shah, E Webber… - Nature …, 2015 - nature.com
Abstract Pro-opiomelanocortin (POMC)-and agouti-related peptide (AgRP)-expressing
neurons of the arcuate nucleus of the hypothalamus (ARC) are oppositely regulated by …

A distributed network for social cognition enriched for oxytocin receptors

M Mitre, BJ Marlin, JK Schiavo, E Morina… - Journal of …, 2016 - Soc Neuroscience
Oxytocin is a neuropeptide important for social behaviors such as maternal care and parent–
infant bonding. It is believed that oxytocin receptor signaling in the brain is critical for these …

Oxytocin neurons enable social transmission of maternal behaviour

I Carcea, NL Caraballo, BJ Marlin, R Ooyama… - Nature, 2021 - nature.com
Maternal care, including by non-biological parents, is important for offspring survival,,,,,,–.
Oxytocin,,,,,,,–, which is released by the hypothalamic paraventricular nucleus (PVN), is a …