Small-molecule inhibitors, immune checkpoint inhibitors, and more: FDA-approved novel therapeutic drugs for solid tumors from 1991 to 2021

Q Wu, W Qian, X Sun, S Jiang - Journal of hematology & oncology, 2022 - Springer
Abstract The United States Food and Drug Administration (US FDA) has always been a
forerunner in drug evaluation and supervision. Over the past 31 years, 1050 drugs …

EAU-EANM-ESTRO-ESUR-SIOG guidelines on prostate cancer. Part II—2020 update: treatment of relapsing and metastatic prostate cancer

P Cornford, RCN van den Bergh, E Briers… - European urology, 2021 - Elsevier
Objective To present a summary of the 2020 version of the European Association of Urology
(EAU)-European Association of Nuclear Medicine (EANM)-European Society for …

[HTML][HTML] Human prostate cancer bone metastases have an actionable immunosuppressive microenvironment

Y Kfoury, N Baryawno, N Severe, S Mei, K Gustafsson… - Cancer cell, 2021 - cell.com
Bone metastases are devastating complications of cancer. They are particularly common in
prostate cancer (PCa), represent incurable disease, and are refractory to immunotherapy …

Treatment of advanced prostate cancer

MY Teo, DE Rathkopf, P Kantoff - Annual review of medicine, 2019 - annualreviews.org
The therapeutic landscape of prostate cancer has been transformed over the last decade by
new therapeutics, advanced functional imaging, next-generation sequencing, and better use …

[177Lu]-PSMA-617 radionuclide treatment in patients with metastatic castration-resistant prostate cancer (LuPSMA trial): a single-centre, single-arm, phase 2 study

MS Hofman, J Violet, RJ Hicks, J Ferdinandus… - The Lancet …, 2018 - thelancet.com
Background Progressive metastatic castration-resistant prostate cancer is a highly lethal
disorder and new effective therapeutic agents that improve patient outcomes are urgently …

Prostate cancer, version 2.2019, NCCN clinical practice guidelines in oncology

JL Mohler, ES Antonarakis, AJ Armstrong… - Journal of the National …, 2019 - jnccn.org
The NCCN Guidelines for Prostate Cancer include recommendations regarding diagnosis,
risk stratification and workup, treatment options for localized disease, and management of …

[HTML][HTML] Cabazitaxel versus abiraterone or enzalutamide in metastatic prostate cancer

R de Wit, J de Bono, CN Sternberg… - … England Journal of …, 2019 - Mass Medical Soc
Background The efficacy and safety of cabazitaxel, as compared with an androgen-signaling–
targeted inhibitor (abiraterone or enzalutamide), in patients with metastatic castration …

Genetics and biology of prostate cancer

G Wang, D Zhao, DJ Spring… - Genes & …, 2018 - genesdev.cshlp.org
Despite the high long-term survival in localized prostate cancer, metastatic prostate cancer
remains largely incurable even after intensive multimodal therapy. The lethality of advanced …

Abiraterone for prostate cancer not previously treated with hormone therapy

ND James, JS de Bono, MR Spears… - … England Journal of …, 2017 - Mass Medical Soc
Background Abiraterone acetate plus prednisolone improves survival in men with relapsed
prostate cancer. We assessed the effect of this combination in men starting long-term …

[HTML][HTML] Plant-derived anticancer agents: A green anticancer approach

J Iqbal, BA Abbasi, T Mahmood, S Kanwal, B Ali… - Asian Pacific Journal of …, 2017 - Elsevier
Cancer is a frightful disease and represents one of the biggest health-care issues for the
human race and demands a proactive strategy for cure. Plants are reservoirs for novel …