Involvement of neural transient receptor potential channels in peripheral inflammation

HA Silverman, A Chen, NL Kravatz… - Frontiers in …, 2020 - frontiersin.org
Transient receptor potential (TRP) channels are a superfamily of non-selective cation
channels that act as polymodal sensors in many tissues throughout mammalian organisms …

Cannabidiol and other non-psychoactive cannabinoids for prevention and treatment of gastrointestinal disorders: useful nutraceuticals?

V Martínez, A Iriondo De-Hond, F Borrelli… - International Journal of …, 2020 - mdpi.com
Cannabis sativa is an aromatic annual flowering plant with several botanical varieties, used
for different purposes, like the production of fibers, the production of oil from the seeds, and …

Cannabis sativa: Much more beyond Δ9-tetrahydrocannabinol

P Alves, C Amaral, N Teixeira… - Pharmacological …, 2020 - Elsevier
Cannabis is the most used illicit drug worldwide and its medicinal use is under discussion,
being regulated in several countries. However, the psychotropic effects of Δ 9 …

[HTML][HTML] The use of cannabinoids in the treatment of inflammatory bowel disease (IBD): a review of the literature

BN Nduma, KA Mofor, J Tatang, C Ekhator, S Ambe… - Cureus, 2023 - ncbi.nlm.nih.gov
Around the world, about 15 to 40% of individuals with inflammatory bowel disease (IBD) rely
on cannabis and cannabinoids to reduce the need for other medications, as well as increase …

Major phytocannabinoids and their related compounds: should we only search for drugs that act on cannabinoid receptors?

LE Filipiuc, DC Ababei, T Alexa-Stratulat, CV Pricope… - Pharmaceutics, 2021 - mdpi.com
The most important discoveries in pharmacology, such as certain classes of analgesics or
chemotherapeutics, started from natural extracts which have been found to have effects in …

[HTML][HTML] Anti-inflammatory natural products modulate interleukins and their related signaling markers in inflammatory bowel disease: A systematic review

GR Gandhi, T Mohana, K Athesh, VE Hillary… - Journal of …, 2023 - Elsevier
This review aims to identify in vivo studies investigating the potential of plant substances and
their natural molecules in managing inflammatory bowel disease (IBD). Specifically, the …

Phytocannabinoid Pharmacology: Medicinal Properties of Cannabis sativa Constituents Aside from the “Big Two”

PB Sampson - Journal of Natural Products, 2020 - ACS Publications
Plant-based therapies date back centuries. Cannabis sativa is one such plant that was used
medicinally up until the early part of the 20th century. Although rich in diverse and interesting …

An overview on synthetic and biological activities of cannabidiol (CBD) and its derivatives

X Wang, H Zhang, Y Liu, Y Xu, B Yang, H Li… - Bioorganic Chemistry, 2023 - Elsevier
Cannabidiol is a class of non-psychoactive plant cannabinoids derived from cannabis
plants. Currently, Epidiolex (Cannabidiol) has been approved by the FDA for the treatment of …

Hesperetin ameliorates DSS-induced colitis by maintaining the epithelial barrier via blocking RIPK3/MLKL necroptosis signaling

J Zhang, H Lei, X Hu, W Dong - European Journal of Pharmacology, 2020 - Elsevier
Hesperetin, a flavonoid from citrus fruits, possess various pharmacological properties,
including anti-inflammatory, anti-oxidative, anti-tumor potentials. However, the role and its …

TRPA1 role in inflammatory disorders: what is known so far?

L Landini, D Souza Monteiro de Araujo, M Titiz… - International Journal of …, 2022 - mdpi.com
The transient receptor potential ankyrin 1 (TRPA1), a member of the TRP superfamily of
channels, is primarily localized in a subpopulation of primary sensory neurons of the …