Systemic sclerosis is a chronic autoimmune disease of still not fully understood
pathogenesis. Fibrosis, vascular wall damage, and disturbances of innate and acquired …

Opinion statement Systemic sclerosis (SSc) is an autoimmune disease initially recognized
by hand involvement due to characteristic Raynaud's phenomenon (RP), puffy hands, skin …

Objectives The multisystem manifestations of SSc can greatly impact patients' quality of life.
The aim of this study was to identify factors associated with disability in SSc. Methods SSc …

The diagnostic assessment of patients with Interstitial Lung Disease (ILD) can be
challenging due to the large number of possible causes. Moreover, the diagnostic approach …

Systemic sclerosis (SSc) is a complex autoimmune disease characterized by heterogeneous
changes involving numerous organs and systems. The currently available data indicate that …

Objective The aim was to evaluate the effect of a home‐based exercise program on
functional capacity, health‐related quality of life (HRQoL), and disability, in patients with …

Systemic sclerosis (SSc) is a connective tissue disease with an unknown etiology. Clinically,
it is characterized by localized or diffuse skin thickening and fibrosis. The pathogenesis of …

Musculoskeletal (MSK) symptoms in patients with systemic sclerosis (SSc) include articular
involvement (arthralgia, synovitis, contractures), which is often an early phenomenon and …

Objective. To evaluate the efficacy of a three-week period of complex and intensive hand
physical therapy on hand function in patients with systemic sclerosis (SSc). Methods. Thirty …

Objectives: Explain the pathophysiologic basis of scleroderma. Contrast the presentation of
localized versus systemic scleroderma. Contrast the management strategies for localized …