E Pelosi, G Castelli, U Testa - International Journal of Molecular Sciences, 2023 - mdpi.com
In spite of consistent progress at the level of basic research and of clinical treatment, acute myeloid leukemia (AML) still represents an unmet clinical need for adult and pediatric …
DA Pollyea, JK Altman, R Assi, D Bixby… - Journal of the National …, 2023 - jnccn.org
Acute myeloid leukemia (AML) is a heterogeneous hematologic malignancy characterized by the clonal expansion of myeloid blasts in the peripheral blood, bone marrow, and/or other …
J Senapati, WC Fiskus, N Daver, NR Wilson… - Clinical Cancer …, 2023 - AACR
Purpose: Treatment outcomes in patients with relapsed/refractory (R/R) myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) remains dismal. On the basis of both …
HS Murthy, MJ Zhang, K Chen, S Ahmed… - Blood …, 2023 - ashpublications.org
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematological malignancy with a poor prognosis and considered incurable with conventional chemotherapy. Small …
YJ Lee, Y Kim, SH Park, JC Jo - Blood research, 2023 - synapse.koreamed.org
Plasmacytoid dendritic cells (pDCs) are type I interferon-producing cells that modulate immune responses. There are two types of pDC neoplasms: 1) mature pDC proliferation …
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare, aggressive hematologic malignancy with poor outcomes. The World Health Organization (WHO) redefined BDCN as …
A Jain, K Sweet - Journal of the National Comprehensive Cancer …, 2023 - jnccn.org
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematologic malignancy with an aggressive clinical course and poor prognosis. BPDCN is most often characterized …
S Bottardi, T Layne, AC Ramòn, N Quansah… - Frontiers in …, 2024 - frontiersin.org
Inflammation control is critical during the innate immune response. Such response is triggered by the detection of molecules originating from pathogens or damaged host cells by …