Blastic plasmacytoid dendritic cell neoplasm: a comprehensive review in pediatrics, adolescents, and young adults (AYA) and an update of novel therapies

B Cuglievan, J Connors, J He, S Khazal, S Yedururi… - Leukemia, 2023 - nature.com
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematologic malignancy that
can involve the bone marrow, peripheral blood, skin, lymph nodes, and the central nervous …

CD123 a therapeutic target for acute myeloid leukemia and blastic plasmocytoid dendritic neoplasm

E Pelosi, G Castelli, U Testa - International Journal of Molecular Sciences, 2023 - mdpi.com
In spite of consistent progress at the level of basic research and of clinical treatment, acute
myeloid leukemia (AML) still represents an unmet clinical need for adult and pediatric …

Acute myeloid leukemia, version 3.2023, NCCN clinical practice guidelines in oncology

DA Pollyea, JK Altman, R Assi, D Bixby… - Journal of the National …, 2023 - jnccn.org
Acute myeloid leukemia (AML) is a heterogeneous hematologic malignancy characterized
by the clonal expansion of myeloid blasts in the peripheral blood, bone marrow, and/or other …

Phase I results of bromodomain and Extra-terminal inhibitor PLX51107 in combination with azacitidine in patients with Relapsed/Refractory myeloid malignancies

J Senapati, WC Fiskus, N Daver, NR Wilson… - Clinical Cancer …, 2023 - AACR
Purpose: Treatment outcomes in patients with relapsed/refractory (R/R) myelodysplastic
syndrome (MDS) and acute myeloid leukemia (AML) remains dismal. On the basis of both …

Allogeneic hematopoietic cell transplantation for blastic plasmacytoid dendritic cell neoplasm: a CIBMTR analysis

HS Murthy, MJ Zhang, K Chen, S Ahmed… - Blood …, 2023 - ashpublications.org
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematological malignancy
with a poor prognosis and considered incurable with conventional chemotherapy. Small …

[HTML][HTML] Plasmacytoid dendritic cell neoplasms

YJ Lee, Y Kim, SH Park, JC Jo - Blood research, 2023 - synapse.koreamed.org
Plasmacytoid dendritic cells (pDCs) are type I interferon-producing cells that modulate
immune responses. There are two types of pDC neoplasms: 1) mature pDC proliferation …

Blastic Plasmacytoid Dendritic Cell Neoplasm: A Comprehensive Review of the Disease, Central Nervous System Presentations, and Treatment Strategies

S Mehra, J Taylor - Cells, 2024 - mdpi.com
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare, aggressive hematologic
malignancy with poor outcomes. The World Health Organization (WHO) redefined BDCN as …

[PDF][PDF] Blastic plasmacytoid dendritic cell neoplasm: Emerging developments and special considerations for 2023

N Pemmaraju, H Kantarjian - Clin. Adv. Hematol …, 2023 - hematologyandoncology.net
Background Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a highly clinically
aggressive, ultra-rare hematologic malignancy. 1 The worldwide incidence is largely …

Blastic plasmacytoid dendritic cell neoplasm

A Jain, K Sweet - Journal of the National Comprehensive Cancer …, 2023 - jnccn.org
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematologic malignancy
with an aggressive clinical course and poor prognosis. BPDCN is most often characterized …

MNDA, a PYHIN factor involved in transcriptional regulation and apoptosis control in leukocytes

S Bottardi, T Layne, AC Ramòn, N Quansah… - Frontiers in …, 2024 - frontiersin.org
Inflammation control is critical during the innate immune response. Such response is
triggered by the detection of molecules originating from pathogens or damaged host cells by …