The Yin and Yang of exosome isolation methods: conventional practice, microfluidics, and commercial kits

SZ Shirejini, F Inci - Biotechnology Advances, 2022 - Elsevier
Exosomes are a subset of extracellular vesicles released from various cells, and they can be
found in different bodily fluids. Exosomes have been utilized as biomarkers to diagnose …

MicroRNA let-7 and viral infections: focus on mechanisms of action

A Letafati, S Najafi, M Mottahedi, M Karimzadeh… - Cellular & Molecular …, 2022 - Springer
MicroRNAs (miRNAs) are fundamental post-transcriptional modulators of several critical
cellular processes, a number of which are involved in host defense mechanisms. In …

Extracellular vesicles isolated by size-exclusion chromatography present suitability for RNomics analysis in plasma

Y Yang, Y Wang, S Wei, C Zhou, J Yu, G Wang… - Journal of translational …, 2021 - Springer
Abstract Background Extracellular vesicles (EVs), known as cell-derived membranous
structures harboring a variety of biomolecules, have been widely used in liquid biopsy. Due …

Global trend in exosome isolation and application: an update concept in management of diseases

M Omrani, H Beyrampour-Basmenj… - Molecular and Cellular …, 2024 - Springer
Extracellular vesicles (EVs) secreted by various cells offer great potential for use in the
diagnosis and treatment of disease. EVs are heterogeneous membranous vesicles …

Extracellular vesicles and their engineering strategies, delivery systems, and biomedical applications

C Yang, Y Xue, Y Duan, C Mao, M Wan - Journal of Controlled Release, 2024 - Elsevier
Extracellular vesicles are nanoscale vesicles that can be secreted by all cell types, are
intracellular in origin and have the same composition as their parent cells, play a key role in …

Extracellular vesicles in immune system regulation and type 1 diabetes: cell-to-cell communication mediators, disease biomarkers, and promising therapeutic tools

GE Grieco, D Fignani, C Formichi, L Nigi… - Frontiers in …, 2021 - frontiersin.org
Extracellular vesicles (EVs) are generated by cells of origin through complex molecular
mechanisms and released into extracellular environment. Hence, the presence of EVs has …

piRNA associates with immune diseases

M Jiang, X Hong, Y Gao, AT Kho, KG Tantisira… - Cell Communication and …, 2024 - Springer
PIWI-interacting RNA (piRNA) is the most abundant small non-coding RNA in animal cells,
typically 26–31 nucleotides in length and it binds with PIWI proteins, a subfamily of …

A systematic review of extracellular vesicle-derived piwi-interacting RNA in human body fluid and its role in disease progression

TX Goh, SL Tan, MM Roebuck, SH Teo… - … Engineering Part C …, 2022 - liebertpub.com
The state of host cells is reflected in the cargo carried by their extracellular vesicles (EVs).
This makes EV a potential source of biomarkers for human diseases. Piwi-interacting RNA …

Comparison of Extracellular Vesicle Isolation Methods for miRNA Sequencing

M Llorens-Revull, B Martínez-González, J Quer… - International journal of …, 2023 - mdpi.com
MicroRNAs (miRNAs) encapsulated in extracellular vesicles (EVs) are potential diagnostic
and prognostic biomarkers. However, discrepancies in miRNA patterns and their validation …

MicroRNA signature from extracellular vesicles of HCV/HIV co-infected individuals differs from HCV mono-infected

V Cairoli, D Valle-Millares, MC Terrón-Orellano… - Journal of Molecular …, 2023 - Springer
Hepatitis C virus (HCV) coinfection with human immunodeficiency virus (HIV) has a
detrimental impact on disease progression. Increasing evidence points to extracellular …