Here, we addressed the pharmacology and toxicology of synthetic organoselenium
compounds and some naturally occurring organoselenium amino acids. The use of …

The main focus for the development of adenosine targets as analgesics to date has been A
1 Rs due to its antinociceptive profile in various preclinical pain models. The usefulness of …

This paper is the thirty-seventh consecutive installment of the annual review of research
concerning the endogenous opioid system. It summarizes papers published during 2014 …

Parkinson's disease is characterized by the death of dopaminergic neurons, mainly in the
substantia nigra, and causes serious locomotor dysfunctions. It is likely that the oxidative …

The combination of pomegranate seed oil and ketoprofen in nanoemulsions aiming to
improve the antinociceptive effect was evaluated according to the writhing test and …

Selenocyano fragments with different structural characteristics have been successfully
installed into the 3-and 17-position of estradiol through the etherification and esterification of …

Several pathologies, such as pain and inflammation, are modulated by different pathways,
making it necessary to develop drugs capable of modulating different pathways. Based on …

A new quinoline containing selenium, 4‐phenylselenyl‐7‐chloroquinoline (4‐PSQ), was
described and synthetized by our research group. Recently, we demonstrated the potential …

Monosodium glutamate (MSG) is a neuroexcitatory amino acid commonly used as flavoring
of foods. MSG neonatal administration to animals leads to behavioral and physiological …

The present study investigated the antioxidant effect of a new class of quinoline derivatives
(ad) on assays in vitro. Lipid peroxidation, thiol peroxidase-like and free radical scavenging …