New research has indicated that long non-coding RNAs (lncRNAs) play critical roles in a
broad range of biological processes, including the pathogenesis of many complex human …

Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, arising from
immature lymphocytes that show uncontrolled proliferation and arrested differentiation …

Genomic classification has improved risk assignment of pediatric, but not adult B-lineage
acute lymphoblastic leukemia (B-ALL). The international UKALLXII/ECOG-ACRIN E2993 (# …

Resistance to glucocorticoids (GC) is associated with an increased risk of relapse in B-cell
progenitor acute lymphoblastic leukemia (BCP-ALL). Performing transcriptomic and single …

Cure rates for acute lymphoblastic leukemia (ALL), the most common childhood cancer have
steadily improved over the past five decades. This is due to intensifying systemic therapy …

RNA-sequencing (RNA-seq) efforts in acute lymphoblastic leukaemia (ALL) have identified
numerous prognostically significant genomic alterations which can guide diagnostic risk …

PCR of TCR/Ig gene rearrangements is considered the method of choice for minimal
residual disease (MRD) quantification in BCP-ALL, but flow cytometry analysis of leukemia …

The role of Erythroid cells in immune regulation and immunosuppression is one of the
emerging topics in modern immunology that still requires further clarification as Erythroid …

Philadelphia chromosome-like acute lymphoblastic leukemia (Ph-like ALL) is a common
subtype of B-lineage acute lymphoblastic leukemia (B-ALL) with increasing frequency …

Children with Down syndrome (DS, trisomy 21) are at a significantly higher risk of
developing acute leukemia compared to the overall population. Many studies investigating …