[HTML][HTML] Candida albicans—The Virulence Factors and Clinical Manifestations of Infection

J Talapko, M Juzbašić, T Matijević, E Pustijanac… - Journal of Fungi, 2021 - mdpi.com
Candida albicans is a common commensal fungus that colonizes the oropharyngeal cavity,
gastrointestinal and vaginal tract, and healthy individuals' skin. In 50% of the population, C …

Aspergillus fumigatus and Aspergillosis in 2019

JP Latgé, G Chamilos - Clinical microbiology reviews, 2019 - Am Soc Microbiol
Aspergillus fumigatus is a saprotrophic fungus; its primary habitat is the soil. In its ecological
niche, the fungus has learned how to adapt and proliferate in hostile environments. This …

Global guideline for the diagnosis and management of mucormycosis: an initiative of the European Confederation of Medical Mycology in cooperation with the …

OA Cornely, A Alastruey-Izquierdo, D Arenz… - The Lancet infectious …, 2019 - thelancet.com
Mucormycosis is a difficult to diagnose rare disease with high morbidity and mortality.
Diagnosis is often delayed, and disease tends to progress rapidly. Urgent surgical and …

Challenges in the diagnosis and treatment of mucormycosis

A Skiada, C Lass-Floerl, N Klimko, A Ibrahim… - Medical …, 2018 - academic.oup.com
The diagnosis and treatment of mucormycosis are challenging. The incidence of the disease
seems to be increasing. Hematological malignancies are the most common underlying …

[HTML][HTML] Drug-resistant fungi: an emerging challenge threatening our limited antifungal armamentarium

A Arastehfar, T Gabaldón, R Garcia-Rubio, JD Jenks… - Antibiotics, 2020 - mdpi.com
The high clinical mortality and economic burden posed by invasive fungal infections (IFIs),
along with significant agricultural crop loss caused by various fungal species, has resulted in …

Posaconazole versus voriconazole for primary treatment of invasive aspergillosis: a phase 3, randomised, controlled, non-inferiority trial

JA Maertens, G Rahav, DG Lee, A Ponce-de-León… - The Lancet, 2021 - thelancet.com
Background Voriconazole has been recommended as primary treatment for patients with
invasive aspergillosis. Intravenous and tablet formulations of posaconazole that have …

[HTML][HTML] Death after hematopoietic stem cell transplantation: changes over calendar year time, infections and associated factors

J Styczyński, G Tridello, L Koster, S Iacobelli… - Bone marrow …, 2020 - nature.com
Abstract Information on incidence, and factors associated with mortality is a prerequisite to
improve outcome after hematopoietic stem cell transplantation (HSCT). Therefore, 55′ 668 …

[HTML][HTML] Diagnosis of severe respiratory infections in immunocompromised patients

E Azoulay, L Russell, A Van de Louw, V Metaxa… - Intensive care …, 2020 - Springer
An increasing number of critically ill patients are immunocompromised. Acute hypoxemic
respiratory failure (ARF), chiefly due to pulmonary infection, is the leading reason for ICU …

Mucormycosis

G Reid, JP Lynch III, MC Fishbein… - Seminars in respiratory …, 2020 - thieme-connect.com
Mucormycosis is an infection caused by a group of filamentous molds within the order
Mucorales. Infections may result from ingestion of contaminated food, inhalation of spores …

[HTML][HTML] Therapy of mucormycosis

NV Sipsas, MN Gamaletsou, A Anastasopoulou… - Journal of Fungi, 2018 - mdpi.com
Despite the recent introduction of mold-active agents (posaconazole and isavuconazole), in
addition to amphotericin B products, to our armamentarium against mucormycosis, many …