The brain harbors a unique ability to, figuratively speaking, shift its gears. During
wakefulness, the brain is geared fully toward processing information and behaving, while …

The neocortex is the seat of higher cognitive functions and, in evolutionary terms, is the
youngest part of the mammalian brain. Since its origin, the neocortex has expanded in …

Folding of the cerebral cortex is a fundamental milestone of mammalian brain evolution and
is associated with dramatic increases in size and complexity. New animal models, genetic …

The size and extent of folding of the mammalian cerebral cortex are important factors that
influence a species' cognitive abilities and sensorimotor skills. Studies in various animal …

Cortical interneurons display striking differences in shape, physiology, and other attributes,
challenging us to appropriately classify them. We previously suggested that interneuron …

One of the most prominent features of the human brain is the fabulous size of the cerebral
cortex and its intricate folding. Cortical folding takes place during embryonic development …

Evolutionary expansion and complexification of the primate cerebral cortex are largely
linked to the emergence of the outer subventricular zone (OSVZ), a uniquely structured …

Larger brains tend to have more folded cortices, but what makes the cortex fold has
remained unknown. We show that the degree of cortical folding scales uniformly across …

The current understanding of neurological diseases is derived mostly from direct analysis of
patients and from animal models of disease. However, most patient studies do not capture …

The evolutionary expansion of the mammalian neocortex is widely considered to be a basis
of increased cognitive abilities. This expansion is a consequence of the enhanced …