Nitric oxide signalling in cardiovascular health and disease
C Farah, LYM Michel, JL Balligand - Nature Reviews Cardiology, 2018 - nature.com
Nitric oxide (NO) signalling has pleiotropic roles in biology and a crucial function in
cardiovascular homeostasis. Tremendous knowledge has been accumulated on the …
cardiovascular homeostasis. Tremendous knowledge has been accumulated on the …
Sudden cardiac death caused by coronary heart disease
RJ Myerburg, MJ Junttila - Circulation, 2012 - Am Heart Assoc
An association between the anatomic pathology and pathophysiology of coronary
atherosclerosis and sudden cardiac death (SCD) has been long recognized. At the end of …
atherosclerosis and sudden cardiac death (SCD) has been long recognized. At the end of …
[HTML][HTML] Serum neurofilament light levels in normal aging and their association with morphologic brain changes
M Khalil, L Pirpamer, E Hofer, MM Voortman… - Nature …, 2020 - nature.com
Neurofilament light (NfL) protein is a marker of neuro-axonal damage and can be measured
not only in cerebrospinal fluid but also in serum, which allows for repeated assessments …
not only in cerebrospinal fluid but also in serum, which allows for repeated assessments …
The Genotype-Tissue Expression (GTEx) pilot analysis: multitissue gene regulation in humans
Understanding the functional consequences of genetic variation, and how it affects complex
human disease and quantitative traits, remains a critical challenge for biomedicine. We …
human disease and quantitative traits, remains a critical challenge for biomedicine. We …
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis
By combining genome-wide association data from 8,130 individuals with type 2 diabetes
(T2D) and 38,987 controls of European descent and following up previously unidentified …
(T2D) and 38,987 controls of European descent and following up previously unidentified …
Epidemiology and genetics of sudden cardiac death
R Deo, CM Albert - Circulation, 2012 - Am Heart Assoc
Sudden cardiac death (SCD) generally refers to an unexpected death from a cardiovascular
cause in a person with or without preexisting heart disease. The specificity of this definition …
cause in a person with or without preexisting heart disease. The specificity of this definition …
Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death
CR Bezzina, J Barc, Y Mizusawa, CA Remme… - Nature …, 2013 - nature.com
Brugada syndrome is a rare cardiac arrhythmia disorder, causally related to SCN5A
mutations in around 20% of cases,,. Through a genome-wide association study of 312 …
mutations in around 20% of cases,,. Through a genome-wide association study of 312 …
Sudden cardiac death prediction and prevention: report from a National Heart, Lung, and Blood Institute and Heart Rhythm Society Workshop
Despite the significant decline in coronary artery disease (CAD) mortality in the second half
of the 20th century, 1 sudden cardiac death (SCD) continues to claim 250 000 to 300 000 …
of the 20th century, 1 sudden cardiac death (SCD) continues to claim 250 000 to 300 000 …
[HTML][HTML] Genetics of human cardiovascular disease
S Kathiresan, D Srivastava - Cell, 2012 - cell.com
Cardiovascular disease encompasses a range of conditions extending from myocardial
infarction to congenital heart disease, most of which are heritable. Enormous effort has been …
infarction to congenital heart disease, most of which are heritable. Enormous effort has been …
Genetics of sudden cardiac death
CR Bezzina, N Lahrouchi, SG Priori - Circulation research, 2015 - Am Heart Assoc
Sudden cardiac death occurs in a broad spectrum of cardiac pathologies and is an important
cause of mortality in the general population. Genetic studies conducted during the past 20 …
cause of mortality in the general population. Genetic studies conducted during the past 20 …