A Revolutionary Approach for Combating Efflux Transporter-mediated Resistant Epilepsy: Advanced Drug Delivery Systems

M Tonk, I Singh, RJ Sharma… - Current Pharmaceutical …, 2025 - benthamdirect.com
Epilepsy is a persistent neurological condition that affects 60 million individuals globally,
with recurrent spontaneous seizures affecting 80% of patients. Antiepileptic drugs (AEDs) …

Assessment of cerebral drug occupancy in humans using a single PET-scan: A [11C] UCB-J PET study

MR Marstrand-Joergensen, GL Laurell… - European Journal of …, 2024 - Springer
Purpose Here, we evaluate a PET displacement model with a Single-step and Numerical
solution in healthy individuals using the synaptic vesicle glycoprotein (SV2A) PET-tracer [11 …

Development and Validation of a Prediction Model for Initial Seizure Episodes During Hospitalization of Icu Patients: A Retrospective Analysis of the Eicu …

N Cheng, J Wang, Z Hui, J Chen, A Gao - Available at SSRN 5046357 - papers.ssrn.com
BackgroundWe aimed to develop and validate predictive models for initial seizure episodes
in ICU patients using various machine learning algorithms. MethodsUsing the extensive …