Fungal diseases represent an important paradigm in immunology, as they can result from
either a lack of recognition by the immune system or overactivation of the inflammatory …

Evidence has increasingly shown that the lungs are a major site of immune regulation. A
robust and highly regulated immune response in the lung protects the host from pathogen …

Only a handful of the more than 100,000 fungal species on our planet cause disease in
humans, yet the number of life-threatening fungal infections in patients has recently …

The fungus Cryptococcus is a major cause of meningoencephalitis in HIV-infected as well as
HIV-uninfected individuals with mortalities in developed countries of 20% and 30 …

Cryptococcus neoformans is a fungal pathogen with worldwide distribution. Serological
studies of human populations show a high prevalence of human infection, which rarely …

Cryptococcus species, the etiological agents of cryptococcosis, are encapsulated fungal
yeasts that predominantly cause disease in immunocompromised individuals, and are …

Cryptococcus neoformans, the predominant etiological agent of cryptococcosis, is an
opportunistic fungal pathogen that primarily affects AIDS patients and patients undergoing …

Extracellular vesicles (EVs) released by eukaryotes, archaea, and bacteria contain proteins,
lipids, polysaccharides, and other molecules. The cargo analysis of EVs shows that they …

Experimental pulmonary Cryptococcus neoformans infection in BALB/c mice is associated
with polarized Th2-type cytokine production, alternative macrophage activation, and severe …

ABSTRACT A vaccine capable of protecting at-risk persons against infections due to
Cryptococcus neoformans and Cryptococcus gattii could reduce the substantial global …