Tumor angiogenesis and anti-angiogenic strategies for cancer treatment

RI Teleanu, C Chircov, AM Grumezescu… - Journal of clinical …, 2019 - mdpi.com
Angiogenesis is the process through which novel blood vessels are formed from pre-existing
ones and it is involved in both physiological and pathological processes of the body …

Involvement of mitochondrial dynamics and mitophagy in diabetic endothelial dysfunction and cardiac microvascular injury

X Zhang, H Zhou, X Chang - Archives of Toxicology, 2023 - Springer
Endothelial cells (ECs), found in the innermost layer of blood vessels, are crucial for
maintaining the structure and function of coronary microcirculation. Dysregulated coronary …

BMP6/TAZ-Hippo signaling modulates angiogenesis and endothelial cell response to VEGF

HH Pulkkinen, M Kiema, JP Lappalainen… - Angiogenesis, 2021 - Springer
Abstract The BMP/TGFβ-Smad, Notch and VEGF signaling guides formation of endothelial
tip and stalk cells. However, the crosstalk of bone morphogenetic proteins (BMPs) and …

Role of vascular endothelial growth factor as a critical neurotrophic factor for the survival and physiology of motoneurons

PM Calvo, RG Hernández, RR de la Cruz… - Neural Regeneration …, 2023 - journals.lww.com
Vascular endothelial growth factor (VEGF) was discovered by its angiogenic activity.
However, during evolution, it appeared earlier as a neurotrophic factor required for the …

β-hydroxybutyrate antagonizes aortic endothelial injury by promoting generation of VEGF in diabetic rats

X Wu, D Miao, Z Liu, K Liu, B Zhang, J Li, Y Li, J Qi - Tissue and Cell, 2020 - Elsevier
Endothelial injury is regarded as the initial pathological process in diabetic vascular
diseases, but effective therapy has not yet been identified. Although β-hydroxybutyrate plays …

Effect of plasma-derived extracellular vesicles on angiogenesis and the ensuing proliferative diabetic retinopathy through a miR-30b-dependent mechanism

P Wang, C Li, Y Deng, Q Yu, X Meng, T Jiang… - Diabetology & Metabolic …, 2022 - Springer
Background/purpose Proliferative diabetic retinopathy (PDR) is a major diabetic
microvascular complication, characterized by pathological angiogenesis. This study sets out …

Pressure overload generates a cardiac-specific profile of inflammatory mediators

M O'Brien, CF Baicu, AO Van Laer… - American Journal …, 2020 - journals.physiology.org
Mechanisms that contribute to myocardial fibrosis, particularly in response to left ventricular
pressure overload (LVPO), remain poorly defined. To test the hypothesis that a myocardial …

COVID-19, vascular endothelial growth factor (VEGF) and iodide

M Turkia - Vascular endothelial growth factor (VEGF) and iodide …, 2020 - papers.ssrn.com
COVID-19, vascular endothelial growth factor (VEGF) and iodide Page 1 COVID-19, vascular
endothelial growth factor (VEGF) and iodide Mika Turkia1 1M.Sc., mika.turkia@alumni.helsinki.fi …

Role of angiopoietic coronary endothelial dysfunction in the pathogenesis of ischemic cardiomyopathy

SP Chumakova, OI Urazova, VM Shipulin, SL Andreev… - Biomedicines, 2023 - mdpi.com
Background: The angiopoietic endothelial dysfunction in ischemic cardiomyopathy (ICMP)
remains unexplored. Aim: The identification of the imbalance of endothelial dysfunction …

Molecular biomarkers of cantharidin‐induced cardiotoxicity in Sprague‐Dawley rats: Troponin T, vascular endothelial growth factor and hypoxia inducible factor‐1α

Z Youyou, Y Yalei, Z Jie, G Chuhuai… - Journal of Applied …, 2020 - Wiley Online Library
Early diagnosis of cantharidin‐induced myocardial injury is the key to reduce the fatality rate
in clinical practice. The purpose of the present study was to explore biomarkers that can be …