Background The devastating public health impact of malaria has prompted the need for
effective interventions. Malaria control gained traction after the introduction of artemisinin …

Sarco/endoplasmic reticulum Ca 2+-ATPases (SERCAs) are increasingly being studied for
therapeutic interventions in the fields of cancer, heart disease, and infection. Our suggestion …

Here, we report the application of a portable sequencer, MinION, for genotyping the malaria
parasite Plasmodium falciparum. In the present study, an amplicon mixture of nine …

Background. As K13 propeller mutations have been recently reported to serve as molecular
markers, assessment of K13 propeller polymorphisms in multidrug-resistant gene in isolates …

Abstract Background The Plasmodium falciparum multidrug resistance 1 (PfMDR1), P.
falciparum Ca 2+-ATPase (PfATP6) and Kelch-13 propeller domain (PfK13) loci are …

Background Drug resistance is one of the main reasons of anti-malarial treatment failures
and impedes malaria containment strategies. As single nucleotide polymorphisms (SNPs) …

Background Resistance to anti-malarial drugs hinders efforts on malaria elimination and
eradication. Following the global spread of chloroquine-resistant parasites, the Republic of …

The development of artemisinin resistance in the Greater Mekong Subregion poses a
significant threat to malaria elimination. Artemisinin-based combination therapies including …

Background: Despite a reduction in the global burden of malaria, the disease remains
responsible for 214 million cases and 438,000 deaths annually with 88% of the mortality …

We aimed to determine the current prevalence of four P. falciparum candidate artemisinin
resistance biomarkers L263E, E431K, A623E, and S769N in the pfatpase6 gene in a high …