Antihyperuricemic and anti-gouty Arthritis Activities of Aurantii Fructus Immaturus carbonisata-derived Carbon Dots

S Wang, Y Zhang, H Kong, M Zhang, J Cheng… - …, 2019 - Taylor & Francis
Aim: To explore the antihyperuricemia and anti-gouty arthritis activities of Aurantii fructus
immaturus carbonisata-derived carbon dots (AFIC-CDs). Materials & methods: The AFIC …

Comparative molecular immunological activity of physiological metal oxide nanoparticle and its anticancer peptide and rna complexes

RK DeLong, J Comer, EN Mathew, M Jaberi-Douraki - Nanomaterials, 2019 - mdpi.com
Currently, there is a great interest in nanoparticle-based vaccine delivery. Recent studies
suggest that nanoparticles when introduced into the biological milieu are not simply passive …

Interaction of Ras Binding Domain (RBD) by chemotherapeutic zinc oxide nanoparticles: Progress towards RAS pathway protein interference

EN Mathew, MN Hurst, B Wang, V Murthy, Y Zhang… - Plos one, 2020 - journals.plos.org
Zinc oxide (ZnO) NP is considered as a nanoscale chemotherapeutic. Thus, the drug
delivery of this inorganic NP is of considerable importance. Ras mutations are common in …

Enzyme nanoscale interactions with manganese zinc sulfide give insight into potential antiviral mechanisms and SARS-CoV-2 inhibition

RK DeLong, H Huber, C Aparicio-Lopez… - ACS Pharmacology & …, 2022 - ACS Publications
Recent interest in nanomedicine has skyrocketed because of mRNA vaccine lipid
nanoparticles (LNPs) against COVID-19. Ironically, despite this success, the innovative …

Evidence of Copper Nanoparticles and Poly I: C Modulating Cas9 Interaction and Cleavage of COR (Conserved Omicron RNA)

LG Karrer, EN Mathew, J Nava-Chavez, A Bhatti… - Bioengineering, 2023 - mdpi.com
Conserved omicron RNA (COR) is a 40 base long 99.9% conserved sequence in SARS-
CoV-2 Omicron variant, predicted to form a stable stem loop, the targeted cleavage of which …

Comparing the effects of physiologically-based metal oxide nanoparticles on ribonucleic acid and RAS/RBD-targeted triplex and aptamer interactions

G Huslig, N Marchell, A Hoffman, S Park… - Biochemical and …, 2019 - Elsevier
Physiological metals such as zinc, magnesium, and nickel facilitate nucleic acid and protein
interactions and stability. In the nanoscale, the impact these have on nucleic acid structure …

[引用][C] Translating nanomedicine to comparative oncology—the case for combining zinc oxide nanomaterials with nucleic acid therapeutic and protein delivery for …

RK DeLong, YH Cheng, P Pearson, Z Lin… - … of Pharmacology and …, 2019 - ASPET

[图书][B] Investigating the biophysical, biochemical, and biological activity of anti-cancer zinc oxide nanoparticle and its physiometacomposite (PMC) nanoparticles

EN Mathew - 2020 - search.proquest.com
Combating melanoma, the most lethal form of skin cancer, our research group works
towards assessing the anticancer potential of zinc oxide (ZnO) nanoparticle and its different …