Malaria, the most prevalent and most pernicious parasitic disease of humans, is estimated to
kill between one and two million people, mainly children, each year. Resistance has …

Following anti-malarial drug treatment asexual malaria parasite killing and clearance
appear to be first order processes. Damaged malaria parasites in circulating erythrocytes …

The epidemiology of malaria in “low-transmission” areas has been underestimated.
Molecular detection methods have revealed higher prevalences of malaria than …

Background A significant reduction in parasite clearance rates following artesunate
treatment of falciparum malaria, and increased failure rates following artemisinin …

A global resurgence of malaria has taken place as a result of a lapse in preventive efforts
and the emergence of resistance to standard antimalarial drugs. New therapies are …

Parasite clearance rates are important measures of anti-malarial drug efficacy. They are
particularly important in the assessment of artemisinin resistance. The slope of the log-linear …

Neutrophils are abundant in the circulation and are one of the immune system's first lines of
defense against infection. There has been substantial work carried out investigating the role …

Antimalarial drug efficacy in uncomplicated malaria should be assessed parasitologically in
large, community-based trials, enrolling the age groups most affected by clinical disease …

Parasite clearance data from 18,699 patients with falciparum malaria treated with an
artemisinin derivative in areas of low (n= 14,539), moderate (n= 2077), and high (n= 2083) …

Antimalarial drug resistance emerges de novo predominantly in areas of low malaria
transmission. Because of the logarithmic distribution of parasite numbers in human malaria …