The aspartic acid metabolic pathway, an exciting and essential pathway in plants

RA Azevedo, M Lancien, PJ Lea - Amino acids, 2006 - Springer
Aspartate is the common precursor of the essential amino acids lysine, threonine,
methionine and isoleucine in higher plants. In addition, aspartate may also be converted to …

Acetohydroxyacid synthase and its role in the biosynthetic pathway for branched-chain amino acids

JA McCourt, RG Duggleby - Amino acids, 2006 - Springer
The branched-chain amino acids are synthesized by plants, fungi and microorganisms, but
not by animals. Therefore, the enzymes of this pathway are potential target sites for the …

Synthesis, crystal structure, bioactivity and DFT calculation of new oxime ester derivatives containing cyclopropane moiety

XH Liu, L Pan, CX Tan, JQ Weng, BL Wang… - Pesticide biochemistry …, 2011 - Elsevier
A new series of oxime esters containing cyclopropane moiety were designed and
synthesized. Their structures were confirmed by 1H NMR, MS and elemental analysis. The …

Synthesis, bioactivity, theoretical and molecular docking study of 1-cyano-N-substituted-cyclopropanecarboxamide as ketol-acid reductoisomerase inhibitor

XH Liu, PQ Chen, BL Wang, YH Li, SH Wang… - Bioorganic & medicinal …, 2007 - Elsevier
Ketol-acid reductoisomerase (KARI; EC 1.1. 1.86) catalyzes the second common step in
branched-chain amino acid biosynthesis. The catalyzed process consists of two stages, the …

High value-added application of sustainable natural forest product α-pinene: synthesis of myrtenal oxime esters as potential KARI inhibitors

G Lin, X Bai, W Duan, B Cen, M Huang… - … Sustainable Chemistry & …, 2019 - ACS Publications
Ketol–acid reductoisomerase catalyzes the second step reaction in the biosynthesis of
essential branched-chain amino acid, and is an important target enzyme to design the safe …

Synthesis of new bioactive aminophosphonates and study of their antioxidant, anti-inflammatory and antibacterial activities as well the assessment of their …

R Damiche, S Chafaa - Journal of Molecular Structure, 2017 - Elsevier
Two new categories of α-aminophosphonates molecules were synthesized and
characterized by UV-Vis, IR, and NMR. Their spectral properties show a perfect …

Synthesis, structure, and biological activity of novel (oxdi/tri) azoles derivatives containing 1, 2, 3-thiadiazole or methyl moiety

XH Liu, L Pan, JQ Weng, CX Tan, YH Li, BL Wang… - Molecular …, 2012 - Springer
To develop novel inhibitors of ketol-acid reductoisomerase, a series of (oxdi/tri) azoles
derivatives was synthesized and characterized by 1 H NMR, MS, elemental analyses, and …

Synthesis, biological activities and SAR studies of new 3-substitutedphenyl-4-substitutedbenzylideneamino-1, 2, 4-triazole Mannich bases and bis-Mannich bases as …

BL Wang, LY Zhang, XH Liu, Y Ma, Y Zhang… - Bioorganic & medicinal …, 2017 - Elsevier
A series of new 3-substitutedphenyl-4-substitutedbenzylideneamino-1, 2, 4-triazole Mannich
bases and bis-Mannich bases were synthesized through Mannich reaction with high yields …

Synthesis and biological activities of novel 5-substituted-1, 3, 4-oxadiazole Mannich bases and bis-Mannich bases as ketol-acid reductoisomerase inhibitors

Y Zhang, XH Liu, YZ Zhan, LY Zhang, ZM Li… - Bioorganic & medicinal …, 2016 - Elsevier
A series of novel 5-substituted-1, 3, 4-oxadiazole Mannich bases and bis-Mannich bases
have been conveniently synthesized in good yields. Their structures were characterized by …

Synthesis, crystal structure, herbicidal activity and mode of action of new cyclopropane-1, 1-dicarboxylic acid analogues

LJ Min, ZH Shen, J Bajsa-Hirschel, CL Cantrell… - Pesticide Biochemistry …, 2022 - Elsevier
A new series of cyclopropane-1, 1-dicarboxylic (CPD) acid analogues were designed and
synthesized. CPD is an inhibitor of ketol-acid reductoisomerase (KARI), an enzyme of the …