Chemoprevention strategies reduce malaria disease and death, but the efficacy of anti-
malarial drugs used for chemoprevention is perennially threatened by drug resistance. This …

Mosquito-borne diseases remain a major cause of morbidity and mortality across the tropical
regions. Despite much progress in the control of malaria, malaria-associated morbidity …

Emergence and spread of resistance in Plasmodium falciparum to the frontline treatment
artemisinin-based combination therapies (ACTs) in the epicenter of multidrug resistance of …

Artemisinin-based combination therapies (ACTs) have become the mainstay for malaria
treatment in almost all malaria endemic settings. Artemisinin derivatives are highly potent …

Background The emergence and spread of multidrug-resistant Plasmodium falciparum in
the Greater Mekong Subregion (GMS) threatens global malaria elimination efforts. Mass …

Summary Background Potentially untreatable Plasmodium falciparum malaria threatens the
Greater Mekong subregion. A previous series of pilot projects in Myanmar, Laos, Cambodia …

Background Although the malaria burden has substantially decreased in sub-Saharan
Africa, progress has stalled. We assessed whether mass administration of ivermectin (a …

Background Primaquine and methylene blue are gametocytocidal compounds that could
prevent Plasmodium falciparum transmission to mosquitoes. We aimed to assess the …

Background Global interest in malaria elimination has prompted research on active test and
treat (TaT) strategies. Methods A systematic review and meta-analysis were conducted to …

Background In low malaria-endemic settings, screening and treatment of individuals in close
proximity to index cases, also known as reactive case detection (RACD), is practised for …