Functional brain imaging in humans has revealed task-specific increases in brain activity
that are associated with various mental activities. In the same studies, mysterious, task …

The brain vasculature has been increasingly recognized as a key player that directs brain
development, regulates homeostasis, and contributes to pathological processes. Following …

Stroke is one of the most common causes of mortality and morbidity in the Western world. It
results from the occlusion of a cerebral artery followed by severe disturbances in blood …

The family of vascular endothelial growth factors (VEGFs) are known for their regulation of
vascularization. In the brain, VEGFs are important regulators of angiogenesis …

The development of the nervous and vascular systems constitutes primary events in the
evolution of the animal kingdom; the former provides electrical stimuli and coordination …

Monitoring subcellular functional and structural changes associated with metabolism is
essential for understanding healthy tissue development and the progression of numerous …

The discovery that brain tissue could potentially be salvaged from ischaemia due to stroke,
has led to major advances in the development of therapies for ischemic stroke. In this …

PURPOSE Our purpose was to evaluate the clinical efficacy, sensitivity, and specificity of
echo-planar diffusion-weighted MR imaging in patients with acute infarction. METHODS We …

Background and Purpose—Continuous arterial spin-labeled perfusion MRI (CASL-PI) uses
electromagnetically labeled arterial blood water as a diffusible tracer to noninvasively …

We prospectively tested the hypothesis that early recovery after ischemic stroke depends on
the ultimate survival of functionally impaired, critically ischemic (ie,“penumbral”) tissue. From …