PM Enriquez-Navas, JW Wojtkowiak, RA Gatenby - Cancer research, 2015 - AACR
The dynamic cancer ecosystem, with its rich temporal and spatial diversity in environmental conditions and heritable cell phenotypes, is remarkably robust to therapeutic perturbations …
Drug resistance mediated by clonal evolution is arguably the biggest problem in cancer therapy today. However, evolving resistance to one drug may come at a cost of decreased …
R Gatenby, J Brown - Cold Spring …, 2018 - perspectivesinmedicine.cshlp.org
Despite continuous deployment of new treatment strategies and agents over many decades, most disseminated cancers remain fatal. Cancer cells, through their access to the vast …
This study was carried out to assess ozone toxicity to 16 populations of Tribolium castaneum (Herbst), 11 populations of Rhyzopertha dominica (F.) and nine populations of Oryzaephilus …
Plant essential oils have been suggested as a suitable alternative for controlling stored pests worldwide. However, very little is known about the physiological or behavioral …
WR Morrison, NL Larson, D Brabec… - Journal of Economic …, 2019 - academic.oup.com
Historically, stored product insect pest management has been based around the use of methyl bromide and phosphine as fumigants. However, methyl bromide has been phased …
K Haddi, MV Mendes, MS Barcellos, J Lino-Neto… - PloS one, 2016 - journals.plos.org
Environmental stress in newly-emerged adult insects can have dramatic consequences on their life traits (eg, dispersion, survival and reproduction) as adults. For instance, insects …
Essential oils have been suggested as suitable alternatives for controlling insect pests. However, the potential adaptive responses elicited in insects for mitigating the actions of …
Target-site mutations and changes in insect metabolism or behavior are common mechanisms in insecticide-resistant insects. The co-occurrence of such mechanisms in a …