Background. Alzheimer's disease (AD) is a progressive neurodegenerative disorder
affecting many individuals worldwide with no effective treatment to date. AD is characterized …

The Alzheimer center of the VU University Medical Center opened in 2000 and was initiated
to combine both patient care and research. Together, to date, all patients forming the …

A 'frontal variant of Alzheimer's disease'has been described in patients with predominant
behavioural or dysexecutive deficits caused by Alzheimer's disease pathology. The …

Objectives The aim of this article was to review the current role of brain PET in the diagnosis
of Alzheimer dementia. The characteristic patterns of glucose metabolism on brain FDG-PET …

Objective: Using data from the Alzheimer's Disease Neuroimaging Initiative (ADNI)
population, we examined (1) cross‐sectional relationships between amyloid deposition …

Positron emission tomography (PET) of brain amyloid β is a technology that is becoming
more available, but its clinical utility in medical practice requires careful definition. To …

Since its opening in 2000, patient care and research go hand in hand at the Alzheimer
center of the VU University Medical Center, both organized in such a way that they mutually …

Alzheimer's disease (AD) is a neurodegenerative disease causing progressive cognitive
decline until eventual death. AD affects millions of individuals worldwide in the absence of …

Aβ Immunotherapy is a promising therapeutic approach for Alzheimer's disease. Preclinical
studies demonstrate that plaque prevention is possible; however, the more relevant …

Alzheimer's disease (AD) can present with distinct clinical variants. Identifying the earliest
neurodegenerative changes associated with each variant has implications for early …