Sepsis is a systemic inflammatory response syndrome caused by an infection. Toll-like
receptor 4 (TLR4) is activated by endogenous molecules released by injured or necrotic …

Microglia is a heterogeneous population that mediates neuroinflammation in the central
nervous system (CNS) and plays a crucial role in developing neuropathic pain. FKBP5 …

Background: Neglected tropical diseases (NTDs), including leishmaniasis, trypanosomiasis,
and schistosomiasis, impose a significant public health burden, especially in developing …

Immunogenic cell death (ICD) is a form of programmed cell death with a strong sense of
inflammatory detection, whose powerful situational awareness can cause the reactivation of …

Cardiac dysfunction caused by sepsis is the predominant reason for death in patients with
sepsis. However, the effective drugs for its prevention and the molecular mechanisms …

Background: Excessive inflammation results in severe tissue damage as well as serious
acute or chronic disorders, and extensive research has focused on finding new anti …

Arsenic, a poisonous metalloid element, is linked to liver diseases, but the exact
mechanisms for this process are not yet to be completely elucidated. Toll like receptor 4 …

Sepsis is a life-threatening syndrome caused by a dysregulated immune response. A large
number of adaptor proteins have been found to play a pivotal role in sepsis via protein …

Toll-like receptor 4 (TLR4) is pivotal as an innate immune receptor, playing a critical role in
mediating neuropathic pain and drug addiction through its regulation of the …

Abstract Toll-like receptor 4 (TLR4) plays a vital role in the innate immune response, but its
overactivation has been associated with several diseases, such as aggressive progression …