Laminin (Ln) and collagen are multifunctional glycoproteins that play an important role in
cellular morphogenesis, cell signalling, tissue repair and cell migration. These proteins are …

Enolase is a glycolytic enzyme, which catalyzes the inter-conversion of 2-phosphoglycerate
to phosphoenolpyruvate. Altered expression of this enzyme is frequently observed in cancer …

Moonlighting proteins are defined as proteins with two or more functions that are unrelated
and independent to each other, so that inactivation of one of them should not affect the …

Microorganisms release effector molecules that modulate the host machinery enabling
survival, replication, and dissemination of a pathogen. Here we characterized the …

Background: Paracoccidioidomycosis (PCM) is a chronic disease that causes sequelae and
requires prolonged treatment; therefore, new therapeutic approaches are necessary. In view …

Pathogens have developed particular strategies to infect and invade their hosts. Amongst
these strategies' figures the modulation of several components of the innate immune system …

Paracoccidioides brasiliensis and P. lutzii are etiologic agents of paracoccidioidomycosis
(PCM), an important endemic mycosis in Latin America. During its evolution, these fungi …

Classic cell wall components of fungi comprise the polysaccharides glucans and chitin, in
association with glycoproteins and pigments. During the last decade, however, system …

Several microbial molecules are released to the extracellular space in vesicle-like
structures. In pathogenic fungi, these molecules include pigments, polysaccharides, lipids …

An efficient oxidative stress response is important to the fungal pathogen Paracoccidioides
to survive within the human host. In this study, oxidative stress was mimicked by exposure of …