Development of biomaterial scaffold for nerve tissue engineering: Biomaterial mediated neural regeneration

A Subramanian, UM Krishnan… - Journal of biomedical …, 2009 - Springer
Neural tissue repair and regeneration strategies have received a great deal of attention
because it directly affects the quality of the patient's life. There are many scientific challenges …

Controlling the morphology and outgrowth of nerve and neuroglial cells: The effect of surface topography

C Simitzi, A Ranella, E Stratakis - Acta biomaterialia, 2017 - Elsevier
Unlike other tissue types, like epithelial tissue, which consist of cells with a much more
homogeneous structure and function, the nervous tissue spans in a complex multilayer …

The effect of the alignment of electrospun fibrous scaffolds on Schwann cell maturation

SY Chew, R Mi, A Hoke, KW Leong - Biomaterials, 2008 - Elsevier
Peripheral nerve regeneration can be enhanced by the stimulation of formation of bands of
Büngner prior to implantation. Aligned electrospun poly (ε-caprolactone)(PCL) fibers were …

Aligned protein–polymer composite fibers enhance nerve regeneration: A potential tissue‐engineering platform

SY Chew, R Mi, A Hoke… - Advanced functional …, 2007 - Wiley Online Library
Sustained release of proteins from aligned polymeric fibers holds great potential in tissue‐
engineering applications. These protein–polymer composite fibers possess high surface …

Nerve guidance conduits based on double-layered scaffolds of electrospun nanofibers for repairing the peripheral nervous system

J Xie, MR MacEwan, W Liu, N Jesuraj, X Li… - … applied materials & …, 2014 - ACS Publications
Compared to the nerve guidance conduits (NGCs) constructed from a single layer of aligned
nanofibers, bilayer NGCs with random and aligned nanofibers in the outer and inner layers …

[HTML][HTML] Advances of adipose-derived mesenchymal stem cells-based biomaterial scaffolds for oral and maxillofacial tissue engineering

T Liu, J Xu, X Pan, Z Ding, H Xie, X Wang, H Xie - Bioactive materials, 2021 - Elsevier
The management of oral and maxillofacial tissue defects caused by tumors, trauma, and
congenital or acquired deformities has been a major challenge for surgeons over the last …

Biodegradable poly (polyol sebacate) polymers

JP Bruggeman, BJ de Bruin, CJ Bettinger, R Langer - Biomaterials, 2008 - Elsevier
We have developed a family of synthetic biodegradable polymers that are composed of
structural units endogenous to the human metabolism, designated poly (polyol …

[HTML][HTML] Promoting neuron adhesion and growth

MY Laura, ND Leipzig, MS Shoichet - Materials today, 2008 - Elsevier
During nervous system development, the extracellular matrix (ECM) plays a pivotal role
offering anchorage points to maturing neurons and neurites, as well as a permissive …

Spider silk fibres in artificial nerve constructs promote peripheral nerve regeneration

C Allmeling, A Jokuszies, K Reimers, S Kall… - Cell …, 2008 - Wiley Online Library
Objective: In our study, we describe the use of spider silk fibres as a new material in nerve
tissue engineering, in a 20‐mm sciatic nerve defect in rats. Materials and methods: We …

Topographically conductive butterfly wing substrates for directed spiral ganglion neuron growth

H Wei, Z Chen, Y Hu, W Cao, XF Ma, C Zhang, X Gao… - Small, 2021 - Wiley Online Library
Spiral ganglion neuron (SGN) degeneration can lead to severe hearing loss, and the
directional regeneration of SGNs has shown great potential for improving the efficacy of …