Asymmetric synthesis of isoquinoline alkaloids: 2004–2015

M Chrzanowska, A Grajewska… - Chemical …, 2016 - ACS Publications
In the past decade, the asymmetric synthesis of chiral nonracemic isoquinoline alkaloids, a
family of natural products showing a wide range of structural diversity and biological and …

Chiral Oxazolopiperidone Lactams: Versatile Intermediates for the Enantioselective Synthesis of Piperidine‐Containing Natural Products

C Escolano, M Amat, J Bosch - Chemistry–A European Journal, 2006 - Wiley Online Library
Phenylglycinol‐derived oxazolopiperidone lactams are exceptionally versatile building
blocks for the enantioselective construction of structurally diverse piperidine‐containing …

Strategies Based on Aryllithium and N‐Acyliminium Ion Cyclizations for the Stereocontrolled Synthesis of Alkaloids and Related Systems

U Martínez‐Estibalez… - European Journal of …, 2011 - Wiley Online Library
The intramolecular α‐amidoalkylation reactions of aromatic and heteroaromatic ring systems
constitute a versatile approach for the synthesis of nitrogen heterocyles in a …

Diverse asymmetric quinolizidine synthesis: a stereodivergent one‐pot approach

W Zhang, J Franzén - Advanced Synthesis & Catalysis, 2010 - Wiley Online Library
A diverse stereodivergent organocatalytic one‐pot addition/cyclization/annulation sequence
to optically active quinolizidine derivatives from easily available starting materials is …

A Stereodivergent Strategy for the Preparation of Corynantheine and Ipecac Alkaloids, Their Epimers, and Analogues: Efficient Total Synthesis of (−) …

W Zhang, J Bah, A Wohlfarth… - Chemistry–A European …, 2011 - Wiley Online Library
Here we present a general and common catalytic asymmetric strategy for the total and
formal synthesis of a broad number of optically active natural products from the …

Diastereoselective Syntheses of Indoloquinolizidines by a Pictet− Spengler/Lactamization Cascade

H Fang, X Wu, L Nie, X Dai, J Chen, W Cao… - Organic …, 2010 - ACS Publications
An expedient diastereoselective synthesis of highly functionalized indolo [2, 3-α]
quinolizidines adopting a cis H2/H12b geometry has been realized by a Pictet− Spengler …

Straightforward Methodology for the Enantioselective Synthesis of Benzo[a]- and Indolo[2,3-a]quinolizidines

M Amat, MMM Santos, O Bassas, N Llor… - The Journal of …, 2007 - ACS Publications
An enantioselective two-step route to substituted benzo [a]-and indolo [2, 3-a] quinolizidines
has been developed. It consists of (i) a stereoselective cyclocondensation of a racemic or …

General and Efficient Organocatalytic Synthesis of Indoloquinolizidines, Pyridoquinazolines and Quinazolinones through a One‐Pot Domino Michael Addition …

M Rueping, CMR Volla, M Bolte… - Advanced Synthesis & …, 2011 - Wiley Online Library
An asymmetric organocatalyzed reaction sequence involving a Michael addition of various
1, 3‐dicarbonyl compounds to α, β‐unsaturated aldehydes with subsequent …

Concise Enantiospecific, Stereoselective Syntheses of (+)-Crispine A and Its (−)-Antipode

M Gurram, B Gyimóthy, R Wang, SQ Lam… - The Journal of …, 2011 - ACS Publications
An enantiospecific and stereoselective total synthesis of the natural product (+)-crispine A
has been demonstrated employing a Pictet− Spengler bis-cyclization reaction between …

Organocatalytic Enantioselective Functionalization of Cyclic α-Hydroxyamides: Access to Chiral Cyclic Imides and Azapolycyclic Compounds

XQ Zhang, YR Ma, YK Liu - Organic Letters, 2023 - ACS Publications
A highly efficient enantioselective enamine-catalyzed asymmetric conjugate addition has
been developed to directly convert unfunctionalized cyclic α-hydroxyamides into chiral cyclic …