Pharmacokinetic boosting of calcineurin inhibitors in transplantation: Pros, cons, and perspectives

S Pattanaik, C Monchaud - Therapeutic Drug Monitoring, 2025 - journals.lww.com
The concept of pharmacokinetic (PK) boosting of calcineurin inhibitors (CNI) emerged after
the FDA approval of cyclosporine-A. Several studies followed, and the proof of concept was …

Assessing the Utility of a Genotype‐Guided Tacrolimus Equation in African American Kidney Transplant Recipients: A Single Institution Retrospective Study

JE Obayemi, L Callans, N Nair, H Gao… - The Journal of …, 2024 - Wiley Online Library
Tacrolimus metabolism is heavily influenced by the CYP3A5 genotype, which varies widely
among African Americans (AA). We aimed to assess the performance of a published …