To prevent the destruction of tissues owing to excessive and/or inappropriate immune
responses, immune cells are under strict check by various regulatory mechanisms at …

Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) affects systemic
small vessels and is accompanied by the presence of ANCAs in the serum. This disease …

INTRODUCTION Glial cells of the central nervous system (CNS), including astrocytes and
microglia, play critical roles in development, tissue repair, and homeostasis. However …

Background Systemic lupus erythematosus (SLE) is a multisystemic, chronic inflammatory
disease characterized by destructive systemic organ involvement, which could cause the …

Simple Summary Since the targeting of a single pro-angiogenic factor fails to improve
oncological disease outcome, significant efforts have been made to identify new pro …

The central nervous system (CNS) and the immune system are both intricate and highly
organized systems that regulate the entire body, with both sharing certain common features …

Abnormal activation of synovial fibroblasts (SFs) plays an important role in rheumatoid
arthritis (RA), the mechanism of which remains unknown. The purpose of our study is to …

Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis is an autoimmune
disorder which affects small-and, to a lesser degree, medium-sized vessels. ANCA …

Cell-cell communication is pivotal to guide embryo development, as well as to maintain adult
tissues homeostasis and control immune response. Among extracellular factors responsible …

Autism spectrum disorder (ASD) is a pervasive disorder that most frequently manifests in
early childhood and lasts for their entire lifespan. Several behavioural traits characterise the …