Design, Synthesis, and Biological Activity Evaluation of Novel AZT and Adenosine‐Derived 1, 2, 3‐Triazoles

DA Le, NH Truong, VD Vu, TH Doan, MT Le… - Journal of …, 2023 - Wiley Online Library
CuSO4/hydrazine hydrate was used as a catalyst system for copper (I)‐catalyzed alkyne‐
azide cycloaddition (CuAAC) of AZT and 5′‐azido adenosine with terminal alkynes to give …

A Literature Review Focusing on the Antiviral Activity of [1, 2, 4] and [1, 2, 3]-triazoles

TA Farghaly, GS Masaret, SM Riyadh… - Mini Reviews in …, 2024 - ingentaconnect.com
Out of a variety of heterocycles, triazole scaffolds have been shown to play a significant part
in a wide array of biological functions. Many drug compounds containing a triazole moiety …

[HTML][HTML] In vitro study of the inhibitory potential of hydroxy-1, 2, 3-triazoles on the replication of ZIKA and chikungunya arboviruses

C Cirne-Santos, RRS Batista, CS Barros… - Results in …, 2024 - Elsevier
Arboviruses, including Zika (ZIKV) and Chikungunya virus (CHIKV), replicate in both
arthropods and vertebrates and are transmitted through mosquito, tick, and sandfly bites …

Bioactivities of Triazolium‐Based N‐Heterocyclic Carbene Salts

J Song, J Zou, J Jin, J Lv, C Mou… - Chemistry–A European …, 2023 - Wiley Online Library
Triazolium salts are precursors of N‐heterocyclic carbenes (NHCs), which have been
extensively used as effective catalysts and ligands for both asymmetric and non …

Design, Synthesis, Molecular Docking Study, and Biological Evaluation of Some New 1, 2, 3-Triazole Derivatives as Anticancer and Antioxidant Agents

NA Abdul-Rida, IH Tarrad - Russian Journal of General Chemistry, 2023 - Springer
Abstract A series of new 1, 2, 3-triazole derivatives was synthesized via a 1, 3-dipolar
cycloaddition reaction. Structures of the synthesized compounds were characterized by IR …

Novel pyrrole based triazole moiety as therapeutic hybrid: synthesis, characterization and anti-Alzheimer potential with molecular mechanism of protein ligand profile

S Khan, T Iqbal, MB Khan, R Hussain, Y Khan… - BMC chemistry, 2024 - Springer
As a springboard to explore novel potent inhibitors of cholinesterase enzymes (AChE and
BChE) responsible for causing Alzheimer disorder, the current study was conducted to …

Design, synthesis, characterization and biological evaluation of coumarin bound 1, 2, 3-triazoles using click chemistry

J Yadav, CP Kaushik, M Ahuja, A Kumar… - Synthetic …, 2024 - Taylor & Francis
In an endeavor to invent new antimalarial and antimicrobial agents, a series of coumarin
bound 1, 4-disubstituted 1, 2, 3-triazoles was synthesized through Cu (I)-promoted click …

[HTML][HTML] SYNTHESIS, CHARACTERIZATION IN SILICO AND IN VITRO STUDY OF NEW 1, 2, 3TRIAZOLE DERIVATIVES AS ANTIOXIDANT AGENTS

NA Abdul-Reda, IH Tarrad - Kimya Problemleri, 2023 - cyberleninka.ru
By the region-selective, a click one-pot reaction a series of new 1, 2, 3-triazole derivatives
were successfully synthesized and evaluated in vitro as antioxidant agents. The molecular …

[PDF][PDF] 新型齐多夫定与4-苯胺喹唑啉骨架拼接产物的合成及体外抗肿瘤活性

梁光平, 王维, 朱绪秀, 梁光焰, 杨俊… - Chin. J. Org …, 2022 - scholar.archive.org
摘要为寻找新型的抗肿瘤药物, 合成了一系列齐多夫定与N-苯基喹唑啉-4-胺骨架的拼接产物.
通过噻唑蓝(MTT) 法评价它们对人肺癌细胞(A549), 人肺癌耐药细胞(A549/DDP) …

Formation of Substituted 1, 2, 4-triazole and evaluation of antifungal activities with ADMET study

WH Salih, AK Alywee - Journal of Survey in Fisheries …, 2023 - sifisheriessciences.com
Abstract A series of 1, 2, 4-triazole derivatives were synthesized from ethyl 4-
hydroxybenzoate with various substituents, and the data came from spectroscopy, infrared …