Targeting the holy triangle of quorum sensing, biofilm formation, and antibiotic resistance in pathogenic bacteria

RV Sionov, D Steinberg - Microorganisms, 2022 - mdpi.com
Chronic and recurrent bacterial infections are frequently associated with the formation of
biofilms on biotic or abiotic materials that are composed of mono-or multi-species cultures of …

[HTML][HTML] The antimicrobial potential of cannabidiol

MAT Blaskovich, AM Kavanagh, AG Elliott… - Communications …, 2021 - nature.com
Antimicrobial resistance threatens the viability of modern medicine, which is largely
dependent on the successful prevention and treatment of bacterial infections. Unfortunately …

Cannabis glandular trichomes: A cellular metabolite factory

CAS Tanney, R Backer, A Geitmann… - Frontiers in Plant …, 2021 - frontiersin.org
Cannabis has been legalized for recreational use in several countries and medical use is
authorized in an expanding list of countries; markets are growing internationally, causing an …

Unique carbazole-oxadiazole derivatives as new potential antibiotics for combating gram-positive and-negative bacteria

YP Xie, N Sangaraiah, JP Meng… - Journal of Medicinal …, 2022 - ACS Publications
Novel carbazole-oxadiazoles were developed as new potential antibacterial agents to
combat dreadful resistance. Some target compounds displayed predominant inhibitory …

Inhibiting fatty acid synthesis overcomes colistin resistance

LA Carfrae, K Rachwalski, S French, R Gordzevich… - Nature …, 2023 - nature.com
Treating multidrug-resistant infections has increasingly relied on last-resort antibiotics,
including polymyxins, for example colistin. As polymyxins are given routinely, the prevalence …

Pharmacological properties, therapeutic potential, and legal status of Cannabis sativa L.: An overview

P Kumar, DK Mahato, M Kamle, R Borah… - Phytotherapy …, 2021 - Wiley Online Library
Marijuana, or Cannabis sativa L., is a common psychoactive plant used for both recreational
and medicinal purposes. In many countries, cannabis‐based medicines have been …

The antimicrobial activity of cannabinoids

JA Karas, LJM Wong, OKA Paulin, AC Mazeh… - Antibiotics, 2020 - mdpi.com
A post-antibiotic world is fast becoming a reality, given the rapid emergence of pathogens
that are resistant to current drugs. Therefore, there is an urgent need to discover new …

Anti-Bacterial Properties of Cannabigerol Toward Streptococcus mutans

M Aqawi, RV Sionov, R Gallily, M Friedman… - Frontiers in …, 2021 - frontiersin.org
Streptococcus mutans (S. mutans) is a gram-positive facultatively anaerobic bacterium and
the most common pathogen associated with tooth caries. The organism is acid tolerant and …

Major phytocannabinoids and their related compounds: should we only search for drugs that act on cannabinoid receptors?

LE Filipiuc, DC Ababei, T Alexa-Stratulat, CV Pricope… - Pharmaceutics, 2021 - mdpi.com
The most important discoveries in pharmacology, such as certain classes of analgesics or
chemotherapeutics, started from natural extracts which have been found to have effects in …

Cannabis: a multifaceted plant with endless potentials

E Fordjour, CF Manful, AA Sey, R Javed… - Frontiers in …, 2023 - frontiersin.org
Cannabis sativa, also known as “hemp” or “weed,” is a versatile plant with various uses in
medicine, agriculture, food, and cosmetics. This review attempts to evaluate the available …