Etiology and therapeutic approach to elevated lactate levels

LW Andersen, J Mackenhauer, JC Roberts… - Mayo Clinic …, 2013 - Elsevier
Lactate levels are commonly evaluated in acutely ill patients. Although most often used in
the context of evaluating shock, lactate levels can be elevated for many reasons. While …

Blood lactate as a predictor for in-hospital mortality in patients admitted acutely to hospital: a systematic review

O Kruse, N Grunnet, C Barfod - Scandinavian journal of trauma …, 2011 - Springer
Background Using blood lactate monitoring for risk assessment in the critically ill patient
remains controversial. Some of the discrepancy is due to uncertainty regarding the …

Severe hyperlactatemia, lactate clearance and mortality in unselected critically ill patients

SA Haas, T Lange, B Saugel, M Petzoldt… - Intensive care …, 2016 - Springer
Purpose Hyperlactatemia may occur for a variety of reasons and is a predictor of poor
clinical outcome. However, only limited data are available on the underlying causes of …

Advanced trauma life support, the evidence for change

JB Kortbeek, SA Al Turki, J Ali, JA Antoine… - Journal of Trauma …, 2008 - journals.lww.com
Abstract The American College of Surgeons Committee on Trauma's Advanced Trauma Life
Support Course is currently taught in 50 countries. The 8th edition has been revised …

Lactate versus non-lactate metabolic acidosis: a retrospective outcome evaluation of critically ill patients

KJ Gunnerson, M Saul, S He, JA Kellum - Critical care, 2006 - Springer
Introduction Acid–base abnormalities are common in the intensive care unit (ICU).
Differences in outcome exist between respiratory and metabolic acidosis in similar pH …

Blood lactate monitoring in critically ill patients: a systematic health technology assessment

TC Jansen, J van Bommel, J Bakker - Critical care medicine, 2009 - journals.lww.com
Objective: To decide whether the use of blood lactate monitoring in critical care practice is
appropriate. We performed a systematic health technology assessment as blood lactate …

The phenomenon of “fluid creep” in acute burn resuscitation

JR Saffle - Journal of burn care & research, 2007 - academic.oup.com
Several reports have documented that modern burn patients receive far more resuscitation
fluid than predicted by the Parkland formula—a phenomenon termed “fluid creep.” This …

Lactate: biomarker and potential therapeutic target

ON Okorie, P Dellinger - Critical care clinics, 2011 - criticalcare.theclinics.com
Critical illness is characterized by disruptions in homeostasis that result in single-or multiple-
organ injury and reversible or irreversible organ dysfunction. To a large extent, the duration …

Lactic acidosis: from sour milk to septic shock

PJ Fall, HM Szerlip - Journal of intensive care medicine, 2005 - journals.sagepub.com
Lactic acidosis is frequently encountered in the intensive care unit. It occurs when there is an
imbalance between production and clearance of lactate. Although lactic acidosis is often …

Occurrence and adverse effect on outcome of hyperlactatemia in the critically ill

H Khosravani, R Shahpori, HT Stelfox, AW Kirkpatrick… - Critical care, 2009 - Springer
Introduction Hyperlactatemia is frequent in critically ill patients and is often used as a marker
of adverse outcome. However, studies to date have focused on selected intensive care unit …